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胎盘慢性炎性疾病的定义、分类及病理学特征

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摘要 狭义的胎盘慢性炎性疾病被定义为一组以多种炎细胞(淋巴细胞、浆细胞、嗜酸性粒细胞和(或)巨噬细胞)浸润胎盘组织,破坏胎盘结构并影响胎盘功能的疾病,包括慢性绒毛炎、慢性蜕膜炎、慢性绒毛膜羊膜炎、慢性组织细胞性绒毛间隙炎和嗜酸性/T细胞绒毛膜血管炎。广义的胎盘慢性炎性疾病还包括与之伴随出现的非炎性疾病,主要指大量绒毛周围纤维蛋白沉积,定义为超过25%的绒毛间隙被纤维蛋白占据。目前,病理学检查仍然是确诊慢性胎盘炎性疾病的唯一手段,提高对该类疾病的认识,对防治再次不良妊娠结局具有重要的临床意义。
出处 《中国产前诊断杂志(电子版)》 2025年第4期7-11,共5页 Chinese Journal of Prenatal Diagnosis(Electronic Version)
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