摘要
目的:探讨经左胸前外侧小切口微创冠状动脉旁路移植术(CABG)治疗冠状动脉多支病变的效果。方法:回顾性分析2023年1月—2024年12月于沧县医院行CABG治疗的冠状动脉多支病变患者80例的临床资料,根据手术方式将其分为对照组(48例)和观察组(32例)。对照组行正中开胸CABG,观察组行经左胸前外侧小切口微创CABG。比较两组围术期指标、心肌标志物水平以及不良心血管事件(MACE)发生率。结果:观察组手术时间比对照组更长(P=0.017),术中出血量比对照组更少(P<0.001);术后1、3 d,观察组肌钙蛋白Ⅰ、肌酸激酶同工酶水平低于对照组(P<0.05);两组术后半年内MACE发生率比较,无统计学差异(P>0.05)。结论:左胸前外侧小切口微创CABG治疗冠状动脉多支病变效果较好,可减少术中出血量,改善心肌标志物水平,且不增加MACE发生率,但手术时间较长。
Objective:To explore the effect of minimally invasive coronary artery bypass grafting(CABG)through small lateral incision on the left chest in the treatment of multi-vessel coronary artery disease.Methods:A retrospective analysis was conducted on the clinical data of eighty patients with multi-vessel coronary artery disease who underwent CABG treatment in Cangxian Hospital from January 2023 to December 2024.They were divided into the control group(48 cases)and the observation group(32 cases)according to the surgical methods.The control group underwent median thoracotomy(CABG),while the observation group received minimally invasive CABG through small lateral incision on the left chest.The perioperative indicators,myocardial marker levels and the incidence of adverse cardiovascular events(MACE)were compared between the two groups.Results:The operation time of the observation group was longer than that of the control group(P=0.017),and the intraoperative blood loss was less than that of the control group(P<0.001).On the 1st and 3rd days after the operation,the levels of troponinⅠand creatine kinase isoenzyme in the observation group were lower than those in the control group(P<0.05).There was no statistically significant difference in the incidence of MACE within half a year after surgery between the two groups(P>0.05).Conclusion:Minimally invasive coronary artery bypass grafting(CABG)with small incision on the left side of the chest has a better therapeutic effect on multi-vessel coronary artery disease.It can reduce intraoperative blood loss,improve myocardial marker levels,and does not increase the incidence of MACE,but the operation time is relatively long.
作者
张韬
Zhang Tao(Cangxian Hospital,Cangzhou 061000,Hebei Province,China)
出处
《中外医药研究》
2025年第30期13-15,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
关键词
经左胸前外侧小切口
冠状动脉旁路移植术
冠状动脉多支病变
心肌标志物
不良心血管事件
Through small incision on the lateral side of the left chest
Coronary artery bypass grafting
Multi-vessel coronary artery disease
Myocardial markers
Adverse cardiovascular events
