摘要
目的探讨计算机断层扫描(CT)引导下经皮肺穿刺活检术(PTLB)后气胸(PTX)和肺出血(PH)的发生率、临床意义及危险因素。方法选取2022年6月-2024年12月皖南医学院第二附属医院呼吸与危重症医学科收治的75例接受CT引导下经皮肺穿刺活检的患者为研究对象,收集患者的人口统计学数据、合并基础疾病、病灶特征、病灶位置、病灶距胸膜距离,穿刺深度及病理结果等资料,分析气胸和肺出血的发生率及类型,并将肺出血和气胸进行亚组分析,比较两组间各项指标的差异,分析PTLB术后出现气胸和肺出血的影响因素。结果PTLB术后气胸的发生率为25.33%,术后肺出血发生率为36.00%。气胸的亚组分析显示两组间是否合并肺气肿及病灶距胸膜距离有统计学差异(P<0.05)。肺出血的亚组分析显示两组间BMI及是否合并糖尿病有统计学差异(P<0.05)。进一步分析显示肺气肿是气胸的独立危险因素(OR=5.057)。结论CT引导下PTLB是一种安全有效的肺活检方法,肺气肿可能是导致操作后气胸的重要原因。
Objective To investigate the incidence,clinical significance and risk factors of pneumothorax(PTX)and pulmonary hemorrhage(PH)after computed tomography(CT)-guided percutaneous transthoracic lung biopsy(PTLB).Methods A total of 75 patients who underwent CT-guided percutaneous transthoracic lung biopsy in the Department of Respiratory and Critical Care Medicine,the Second Affiliated Hospital of Wannan Medical College from June 2022 to December 2024 were selected as the research objects.The demographic data,combined underlying diseases,lesion characteristics,lesion location,distance from the lesion to the pleura,puncture depth and pathological results were collected.The incidence and types of pneumothorax and pulmonary hemorrhage were analyzed.Subgroup analysis of pulmonary hemorrhage and pneumothorax was performed to compare the differences between the two groups.The influencing factors of pneumothorax and pulmonary hemorrhage after PTLB were analyzed.Results The incidence of pneumothorax after PTLB was 25.33%,and the incidence of postoperative pulmonary hemorrhage was 36.00%.Subgroup analysis of pneumothorax showed that there were significant differences in emphysema and distance from the lesion to the pleura between the two groups(P<0.05).Subgroup analysis of pulmonary hemorrhage showed that there were significant differences in BMI and diabetes mellitus between the two groups(P<0.05).Further analysis showed that emphysema was an independent risk factor for pneumothorax(OR=5.057).Conclusion CT-guided PTLB is a safe and effective method for lung biopsy.Emphysema may be an important cause of pneumothorax after operation.
作者
刘璇
王京
马冉冉
高秀峰
LIU Xuan;WANG Jing;MA Ranran;GAO Xiufeng(Department of Respiratory and Critical Care Medicine,the Second Affiliated Hospital of Wannan Medical College,Wuhu 241000,Anhui,China)
出处
《医学信息》
2025年第23期109-112,共4页
Journal of Medical Information
基金
2024年度安徽省卫生健康科研项目(编号:AHWJ2024BAd20009)。
关键词
经皮肺穿刺活检
肺出血
气胸
Percutaneous transthoracic lung biopsy
Pulmonary hemorrhage
Pneumothorax
