摘要
不稳定型心绞痛(Unstable Angina,UA)属于冠心病常见亚型,其病理基础为动脉粥样硬化斑块破裂、血小板聚集及血栓形成。老年人动脉硬化进展快、血管重构能力减弱、伴多种慢性疾病,因此UA发病率与病死率均明显升高。UA西医治疗虽在抗血小板、调脂、介入及血运重建等方面取得显著进展,但在降低复发率及改善心肌微循环方面仍存在不足。中医则从整体观与辨证论治出发,强调“本虚标实”“痰瘀互结”,以益气活血、化痰通络为核心治则,能有效改善症状、提高患者生活质量。近年来,中西医结合在老年不稳定型心绞痛防治中显示出其独特优势,为临床诊疗提供了新思路。因此,本文旨在系统综述老年UA的中西医病因病机及治疗研究进展,为临床诊疗与研究提供参考。
Unstable angina(UA),a common subtype of coronary artery disease,is primarily caused by atherosclerotic plaque rupture,platelet aggregation,and thrombus formation.In elderly patients,rapid progression of arteriosclerosis,impaired vascular remodeling,and the presence of multiple chronic comorbidities contribute to significantly higher incidence and mortality rates of UA.Although modern Western medicine has achieved substantial progress in antiplatelet therapy,lipid regulation,percutaneous coronary intervention,and revascularization,limitations remain in reducing recurrence rates and improving microcirculatory function.Traditional Chinese Medicine(TCM),guided by the holistic concept and syndrome differentiation,emphasizes the pathogenesis of“root deficiency and branch excess”and the interaction of“phlegm and blood stasis.”Therapeutic principles such as tonifying qi,activating blood circulation,resolving phlegm,and unblocking the collaterals have been shown to effectively alleviate symptoms and enhance patients’quality of life.In recent years,integrated Chinese and Western medicine has demonstrated unique advantages in the prevention and treatment of UA in the elderly,offering new perspectives for clinical management.This review aims to systematically summarize the etiology,pathogenesis,and therapeutic progress of UA in elderly patients from both Chinese and Western medical perspectives,providing a reference for clinical practice and future research.
作者
武璐亚
温奕超
Wu Luya;Wen Yichao(The Fourth Clinical Medical College of Xinjiang Medical University,Urumqi,Xinjiang 830011,China)
出处
《首都食品与医药》
2026年第1期14-18,共5页
Capital Food Medicine
关键词
老年不稳定型心绞痛
中西医病因病机
治疗研究进展
综述
elderly unstable angina
integrated Chinese and Western medicine etiology and pathogenesis
Therapeutic progress
review
