摘要
胃癌是全球病死率最高的癌症之一,根据Correa模型,胃癌的发生常经历一个完整的“炎–癌”转化过程。临床早期诊断、治疗胃癌及改善胃癌患者的预后具有重要意义。国医大师李佃贵教授结合多年临床经验创新性提出“浊毒理论”,认为“浊为毒之渐,毒为浊之深”,与“炎–癌”转化特性有相似之处,并针对胃“炎–癌”病机的演化特点提出以化浊解毒为基本治法,在延缓胃“炎–癌”进程中取得了满意的疗效。近年来,随着中西医结合诊疗模式的深化,现代医家将内镜、病理等微观指标融入中医脾胃病“病–证”结合治疗体系中,形成了“病–证–镜”合参诊疗的新模式。“浊毒理论”与“病–证–镜”合参诊疗是将现代医学的检查手段与中医传统四诊相结合,将微观指标视为中医四诊的延伸与补充,使得中医辨证论治过程量化和规范化,不仅可丰富中医的辨证理论,也可为现代医学提供新的视角和方法,促进中医辨证的规范化和中医药干预胃“炎–癌”转化的疗效量化研究的发展。因此,将中医宏观辨证与现代内镜技术相结合,探析常见脾胃病的病机演化特点,以合理指导临床治疗,改善患者预后,推动中西医结合诊疗的进步与发展。
Gastric cancer is one of the cancers with the highest mortality rate in the world.According to the Correa model,gastric cancer often undergoes a complete“inflammation-cancer”transformation process.It is of great significance for early clinical diagnosis and treatment of gastric cancer as well as ameliorating the prognosis of gastric cancer patients.Prof.LI Diangui,a traditional Chinese medicine(TCM)master,innovatively puts forward the“turbid toxicity theory”bases on many years of clinical experience,and believes that“turbidity is the gradual development of toxicity,and toxicity is the deepening of turbidity”,which is similar to the characteristics of“inflammation-cancer”transformation.In view of the evolutionary characteristics of gastric inflammation transforming into gastric cancer,the basic treatment method of removing turbidity and detoxifying is proposed by the professor,which has achieved satisfactory curative effects in delaying the progression of“inflammation-cancer”transformation.In recent years,with the deepening of the diagnosis and treatment mode of the integrative medicine,modern medical doctors have integrated endoscopy,pathology and other microscopic indicators into the“disease-syndrome”synergistic treatment system of TCM spleen and gastric diseases,forming a new diagnosis and treatment model of“disease-syndrome-gastroscope”synergia.“Turbid toxicity theory”and“disease-syndrome-gastroscope”synergistic diagnosis and treatment mode combines the detection means of modern medicine with the four diagnostic methods of TCM,and regards micro-indicators as an extension and supplement of the four diagnostic methods of TCM,which makes the process of TCM syndrome differentiation and treatment quantitative and standardized.This diagnostic and therapeutic approach not only can enrich the theory of TCM syndrome differentiation and treatment,but also provides new perspectives and methods for modern medicine,and promotes the normalization of TCM syndrome differentiation and the development of quantitative research on the therapeutic efficacy of TCM intervention in the transformation of“inflammation-cancer”of gastric diseases.Therefore,the macroscopic syndrome differentiation of TCM and modern endoscopic technique are combined to analyze the pathogenesis and evolutionary characteristics of common spleen and gastric diseases,so as to rationally guide clinical practice and ameliorate the prognosis of patients,and promote the progress and development of the diagnosis and treatment in the integrative medicine.
出处
《中医临床研究》
2025年第26期33-37,共5页
Clinical Journal Of Chinese Medicine
基金
福建省2023年省级临床重点专科建设项目(闽卫医政函〔2023〕1163号)
福建中医药大学林平中医药传承工作室(闽中医〔2023〕56号)。
关键词
浊毒理论
“病–证–镜”合参
胃“炎–癌”转化
病机
Turbid toxicity theory
Disease-syndrome-gastroscope synergy
“Inflammation-cancer”transition of gastric diseases
Pathogenesis
