摘要
目的:运用数据挖掘技术探讨电针(EA)及经颅直流电刺激(t DCS)治疗抑郁症的刺激参数应用规律。方法:检索知网、PubMed等中英文数据库中涉及EA及t DCS治疗抑郁症的期刊文献,检索时间为2015年1月1日至2025年1月1日。偏倚风险评价后建立文献数据库,对提取数据进行描述性分析、关联规则分析和聚类分析。结果:共纳入文献138篇,提取139组数据。电针治疗抑郁症常用脉冲波形为疏密波(67.19%)和连续波(31.25%);电针常用频率为2 Hz(20.75%)和2/15 Hz(13.73%),而耳电针常用频率为15 Hz(38.46%)和20 Hz(30.77%);电针刺激强度常以患者耐受为度(66.67%),t DCS刺激强度多为2 m A(73.33%)。在单次治疗时间方面,电针、t DCS均常选择30 min。电针腧穴主要集中在督脉腧穴,以百会、印堂最为常见;其次为经外奇穴,以四神聪最常使用;耳电针常用耳穴心和神门;关联规则和聚类分析结果显示百会、印堂、内关、神门与三阴交之间联系密切;t DCS刺激电极常置于两侧背外侧前额叶区。结论:采用电针、耳电针及tDCS治疗抑郁症需要选择适宜的电刺激参数,尤其要关注刺激频率、刺激穴位(或部位)。
Objective:To explore the application patterns of stimulation parameters in electro-acupuncture(EA)and transcranial direct current stimulation(tDCS)for the treatment of depression using data mining techniques.Methods:Journal articles on EA and tDCS for the treatment of depression were retrieved from Chinese and English databases,including CNKI and PubMed,covering the period from January 1st 2015 to January 1st 2025.After assessing the risk of bias,a literature database was established,and the extracted data were analyzed using descriptive analysis,association rule analysis,and cluster analysis.Results:A total of 138 studies were included,from which 139 datasets were extracted.The commonly used pulse waveforms for EA in treating depression were sparse-dense waves(67.19%)and continuous waves(31.25%).The frequently used EA stimulation frequencies were 2 Hz(20.75%)and 2/15 Hz(13.73%),whereas for auricular EA,the common frequencies were 15 Hz(38.46%)and 20 Hz(30.77%).EA stimulation intensity was usually based on patient tolerance(66.67%),while tDCS intensity was mostly 2 mA(73.33%).For single-session treatment duration,it was commonly 30 mins both for EA and tDCS.EA acupoints were mainly located on the Du meridian,with Baihui(DU20)and Yintang(EX-HN3)being the most frequently used,followed by extraordinary points,with Sishencong(EX-HN1)most applied.Auricular EA commonly targeted the Heart and Shenmen points.Association rules and cluster analyses showed close connections among DU20,EX-HN3,Neiguan(PC6),Shenmen(HT7),and Sanyinjiao(SP6).For tDCS,the stimulation electrodes were usually placed on the bilateral dorsolateral prefrontal cortex.Conclusion:The treatment of depression using EA,auricular EA,and tDCS requires selecting appropriate electrical stimulation parameters,with particular attention to stimulation frequency and the choice of acupoints(or stimulation sites).
作者
田嫒
王雅璇
刘晓玲
石安妮
卢峻
图娅
TIAN Ai;WANG Yaxuan;LIU Xiaoling;SHI Anni;LU Jun;TU Ya(School of Acupuncture-Moxibustion and Tuina,Beijing University of Chinese Medicine,Beijing 100029,China)
出处
《针灸临床杂志》
2025年第11期59-67,共9页
Journal of Clinical Acupuncture and Moxibustion
基金
国家自然科学基金,编号:82174508。
关键词
抑郁症
电针
经颅直流电刺激
刺激参数
数据挖掘
Depression
Electro-acupuncture
Transcranial direct current stimulation
Stimulation parameters
Data mining
