摘要
成人急性中毒是急诊科常见急症,血液灌流是其关键救治手段之一,但国内对血液灌流治疗的灌流器选择尚缺乏统一认识。本共识强调需依据药物/毒物的药代(毒代)动力学特征,结合血液灌流器特性,以及中毒严重程度、并发症及当地医疗条件等因素合理选择灌流器,并针对治疗时机、单次治疗时限等提出了一些建议,以期为临床医生合理选择血液灌流的灌流器治疗成人急性中毒提供参考,进一步规范成人急性中毒的血液灌流治疗流程,以期提高救治成功率。
Adult acute poisoning is a common emergency in the emergency department,and hemoperfusion is one of the key resuscitative treatment methods.However,there is a lack of unified consensus on the selection of hemoperfusion cartridges for hemoperfusion therapy in China.This consensus emphasizes that the selection of hemoperfusion cartridges should be based on the pharmacokinetic or toxicokinetic characteristics of drugs/toxins,combined with the properties of hemoperfusion cartridges,as well as factors such as the severity of poisoning,complications,and local medical conditions.Additionally,it puts forward suggestions on the timing of treatment initiation and single treatment duration.This consensus aims to provide a reference for clinicians in the rational selection of hemoperfusion cartridges for the treatment of adult acute poisoning,further standardize the hemoperfusion treatment process for adult acute poisoning,and thereby improve the success rate of treatment.
出处
《中国急救医学》
2025年第12期1032-1039,共8页
Chinese Journal of Critical Care Medicine
关键词
急性中毒
药代动力学
毒代动力学
血液灌流
灌流器
Acute poisoning
Pharmacokinetics
Toxicokinetics
Hemoperfusion
Hemoperfusion cartridge
