摘要
目的评估并且比较不同微创术式对急性结石性胆囊炎的临床效果。方法选取2022年6月至2024年5月期间收治的104例患者作为研究对象,并按手术方式将其划分为两个组别:观察组(52例)行单孔腹腔镜胆囊切除术,对照组(52例)接受传统三孔腹腔镜手术。研究重点围绕两组患者在围术期相关指标、炎症反应程度、术后疼痛感受及并发症发生情况等方面展开系统比较。结果研究数据显示,观察组患者的手术时间较对照组有所延长,但其在切口大小、术中失血量、术后首次排气时间及住院总时长方面均优于对照组,差异具有统计学意义(P<0.05)。在炎症指标方面,术后第3天两组患者的CRP、IL-6和TNF-α水平均较术前上升,但观察组的上升幅度明显低于对照组(P<0.05)。疼痛评估结果显示,在术后4小时、8小时、24小时及72小时四个时间点,观察组的VAS评分均显著低于对照组(P<0.05)。此外,观察组术后并发症的总体发生率也明显低于对照组(P<0.05)。结论综合分析表明,尽管单孔腹腔镜胆囊切除术在手术时长上不具优势,但其在减小创伤、促进术后康复、降低炎症反应、减轻疼痛及减少并发症等方面展现出显著益处,因而在急性结石性胆囊炎的外科治疗中具有较好的临床应用价值。
Objective To evaluate and compare the clinical effects of different minimally invasive surgical methods on acute calculous cholecystitis.Methods A total of 104 patients admitted from June 2022 to May 2024 were selected as the research subjects and divided into two groups according to the surgical methods:the observation group(52 cases)underwent single-port laparoscopic cholecystectomy,and the control group(52 cases)received traditional three-port laparoscopic surgery.The research focused on conducting a systematic comparison between the two groups of patients in terms of perioperative related indicators,the degree of inflammatory response,postoperative pain perception and the occurrence of complications.Results The results showed that the operation time of the observation group was longer than that of the control group.However,the observation group was superior to the control group in terms of incision size,intraoperative blood loss,time to first postoperative exhaust,and total hospital stay,and the differences were statistically significant(P<0.05).In terms of inflammatory indicators,on the third day after the operation,the levels of CRP,IL-6 and TNF-αin both groups increased compared with those before the operation,but the increase in the observation group was significantly lower than that in the control group(P<0.05).The pain assessment results showed that at the four time points of 4 hours,8 hours,24 hours and 72 hours after the operation,the VAS scores of the observation group were significantly lower than those of the control group(P<0.05).In addition,the overall incidence of postoperative complications in the observation group was also significantly lower than that in the control group(P<0.05).Conclusion Comprehensive analysis indicates that although singleport laparoscopic cholecystectomy does not have an advantage in terms of operation duration,it demonstrates significant benefits in reducing trauma,promoting postoperative recovery,lowering inflammatory responses,alleviating pain,and reducing complications.Therefore,it has good clinical application value in the surgical treatment of acute calculous cholecystitis.
作者
常伟
凡梦琦
李昊
于龙
CHANG Wei;FAN Meng-qi;LI Hao;YU Long(Department of General Surgery,Shangqiu City People's Hospital,Shangqiu 476000,Henan Province,China;Department of General Surgery,the First Affiliated Hospital of Dalian Medical University,Dalian 116000,Liaoning Province,China)
出处
《罕少疾病杂志》
2025年第12期87-90,共4页
Journal of Rare and Uncommon Diseases
基金
国家自然科学基金面上项目(81774082)。
关键词
急性结石性胆囊炎
腹腔镜胆囊切除术
单孔
三孔
炎症因子
疼痛程度
Acute Calculous Cholecystitis
Laparoscopic Cholecystectomy
Isopore
Three Holes
Inflammatory Factors
Pain Level
