摘要
目的研究心脏手术风险评估欧洲系统(EuroSCO RE)评分在心脏手术患者医院感染中的预测价值。方法选择我院2020年7月至2021年1月纳入的心脏手术患者85例,按术后是否发生感染划分成两组,其中34例发生感染者作为A组,另51例未发生感染者作为B组,收集并整理两组的临床资料,对比两组术后白介素-6(IL-6)、白介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)、白细胞计数(WBC),对比两组性别、年龄、体质量、手术时长、手术方式、体外循环时长、主动脉阻断时长、住院时长、抗菌药物使用时长、重症病房监护时长、EuroSCO RE评分,选择Pearson分析EuroSCO RE与住院时长、抗菌药物使用时长、重症病房监护时长、IL-6、IL-8、TNF-α、WBC、CRP的相关性。结果A组IL-6、IL-8、TNF-α、WBC、CRP均高于B组(P<0.05)。两组在性别、年龄、体质量、手术时长、手术方式、体外循环时长、主动脉阻断时长上无显著差异(P>0.05),但A组EuroSCO RE、住院时长、抗菌药物使用时长、重症病房监护时长均高于B组(P<0.05)。经Pearson分析发现EuroSCO RE与住院时长、抗菌药物使用时长、重症病房监护时长、IL-6、IL-8、TNF-α、WBC、CRP均呈现正相关性(P<0.05)。结论EuroSCO RE评分能够预测心脏手术的风险,并对其感染情况进行评估,尽早予以对应措施,以此达到缩短住院时长的目的。
Objective To evaluate the predictive value of the European System for Cardiac Surgery Risk Assessment(EuroSCO RE)score in hospital-acquired infections(HAI)among cardiac surgery patients.Methods A total of 85 cardiac surgery patients admitted to our hospital from July 2020 to January 2021 were divided into two groups based on postoperative infection status:Group A(34 infected patients)and Group B(51 uninfected patients).Clinical data were collected and analyzed,including postoperative levels of interleukin-6(IL-6),interleukin-8(IL-8),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),and white blood cell count(WBC).The two groups were also compared in terms of gender,age,body weight,surgical duration,surgical approach,extracorporeal circulation time,aortic cross-clamping duration,hospital stay duration,antibiotic use duration,intensive care unit(ICU)monitoring duration,and EuroSCO RE score.Pearson correlation analysis was performed to assess the relationships between EuroSCO RE scores and hospital stay duration,antibiotic use duration,ICU monitoring duration,as well as IL-6,IL-8,TNF-α,WBC,and CRP levels.Results The A group showed significantly higher levels of IL-6,IL-8,TNF-α,WBC,and CRP compared to the B group(P<0.05).No significant differences were observed between the two groups in gender,age,body weight,surgical duration,surgical approach,extracorporeal circulation time,or aortic cross-clamping duration(P>0.05).However,the A group exhibited higher EuroSCO RE scores,hospital stay duration,antibiotic use duration,and ICU monitoring duration compared to the B group(P<0.05).Pearson analysis revealed that EuroSCO RE scores were positively correlated with hospitalization duration,duration of antimicrobial use,intensive care unit(ICU)stay,and levels of IL-6,IL-8,TNF-α,WBC,and CRP(P<0.05).Conclusion The study concluded that EuroSCO RE scores can predict cardiac surgery risks and assess infection status,enabling timely intervention to reduce hospitalization duration.
作者
颜宇
黄淑珍
YAN Yu;HUANG Shu-zhen(Operating Room,First Affiliated Hospital of Nanchang University,Nanchang 330006,Jiangxi Province,China)
出处
《罕少疾病杂志》
2025年第12期60-62,共3页
Journal of Rare and Uncommon Diseases
基金
江西省卫生计生委科技计划(20195141)。
关键词
医院感染
心脏手术风险评估欧洲系统
炎性指标
Hospital Infection
European System for Risk Assessment of Cardiac Surgery
Inflammatory Markers
