摘要
目的:探究彩色多普勒超声在缺血性脑卒中患者颈动脉狭窄诊断中的应用。方法:纳入2024年3月1日~2025年3月1日收治的60例缺血性脑卒中患者。所有患者通过磁共振血管成像诊断,根据患者颈动脉狭窄程度分为轻中度组(n=40,狭窄率<70%)与重度组(n=20,狭窄率≥70%)。对比两组基线资料与临床指标,对比两组彩色多普勒超声结果,采用二元logistic回归分析缺血性脑卒中患者重度颈动脉狭窄的影响因素,并通过受试者操作特征曲线分析彩色多普勒超声在诊断缺血性脑卒中患者颈动脉狭窄中的价值。结果:重度组年龄、胆固醇、甘油三酯、低密度脂蛋白、超敏C反应蛋白均显著高于轻中度组(P<0.05);重度组斑块长度、斑块厚度、斑块个数、内膜中层厚度均显著高于轻中度组(P<0.05);胆固醇、甘油三酯、低密度脂蛋白、超敏C反应蛋白、斑块长度、斑块厚度、斑块个数、内膜中层厚度是缺血性脑卒中患者重度颈动脉狭窄的影响因素(P<0.05);以斑块长度、斑块厚度、斑块个数、内膜中层厚度为检验变量,预测重度颈动脉狭窄的曲线下面积为0.801、0.806、0.935、0.854,4项联合预测曲线下面积为0.996,价值更高。结论:彩色多普勒超声能够有效诊断缺血性脑卒中患者颈动脉狭窄程度,斑块长度、斑块厚度、斑块个数、内膜中层厚度异常升高预测患者颈动脉狭窄加重。
Objective:To explore the application of color Doppler ultrasound in the diagnosis of carotid artery stenosis in patients with ischemic stroke.Methods:Included from March 1,2024 to March 1,2025,60 patients with ischemic stroke were admitted.All patients were diagnosed by magnetic resonance angiography.According to the degree of carotid artery stenosis,the patients were divided into mild to moderate group(n=40,stenosis rate<70%)and severe group(n=20,stenosis rate≥70%).The baseline data and clinical indicators of the two groups were compared,and the results of color Doppler ultrasound were compared between the two groups.Binary logistic regression was used to analyze the influencing factors of severe carotid artery stenosis in patients with ischemic stroke,and the value of color Doppler ultrasound in the diagnosis of carotid artery stenosis in patients with ischemic stroke was analyzed by ROC curve.Results:The age,cholesterol,triglyceride,low density lipoprotein and high sensitivity CRP in the severe group were significantly higher than those in the mild and moderate group(P<0.05).The plaque length,plaque thickness,plaque number and IMT in the severe group were significantly higher than those in the mild to moderate group(P<0.05).Cholesterol,triglyceride,low-density lipoprotein,high-sensitivity CRP,plaque length,plaque thickness,plaque number and IMT were the influencing factors of severe carotid stenosis in patients with ischemic stroke(P<0.05).Taking plaque length,plaque thickness,plaque number and IMT as test variables,the AUC of predicting severe carotid stenosis was 0.801,0.806,0.935,0.854,and the AUC of the four combined prediction was 0.996,which was of higher value.Conclusion:Color Doppler ultrasound can effectively diagnose the degree of carotid artery stenosis in patients with ischemic stroke.The abnormal increase of plaque length,plaque thickness,plaque number and IMT can predict the aggravation of carotid artery stenosis.
作者
余小清
彭伟娇
张新
骆平辉
YU Xiao-qing;PENG Wei-jiao;ZHANG Xin;LUO Ping-hui(Department of Ultrasound,Longchuan County Hospital of Traditional Chinese Medicine,Guangdong Heyuan 517300)
出处
《中国医疗器械信息》
2025年第21期109-111,119,共4页
China Medical Device Information
