摘要
目的探究氢氧化钙糊剂联合浓缩生长因子(CGF)应用于年轻恒牙血运重建的效果。方法选择2018年3月—2024年6月在本院确诊的81例年轻恒牙牙髓炎坏死患者,随机数字表法分为对照组(n=40)和联合组(n=41),采用牙髓血运重建术,对照组根管消毒后取氢氧化钙糊剂进行窝洞封闭,联合组在对照组基础上再联用CGF。比较两组临床疗效、咬合力、牙根长、管壁厚度、疼痛情况及不良反应。结果术后12个月,联合组总有效率(95.12%)高于对照组(77.50%)(P<0.05);两组患者的咬合力、牙根长、管壁厚度水平均显著高于术前,且联合组高于对照组(P<0.05);两组患者术后3个月、6个月、9个月、12个月的视觉模拟量表评分均低于术前,且两组同期之间的差异无统计学意义(P>0.05);术后随访期间,两组根尖炎症,根管钙化、牙体变色等总不良反应发生率无明显差异(P>0.05)。结论氢氧化钙糊剂联合CGF治疗年轻恒牙牙髓炎坏死患者,可有效促进患牙牙根生长,提高管壁厚度,提升患者咬合力,未增加额外不良反应,临床疗效显著。
Objective To investigate the effect of calcium hydroxide paste combined with concentrated growth factor(CGF)in the revascularization of young permanent teeth.Methods A total of 81 young patients diagnosed with pulpitis and pulp necrosis of permanent teeth in our hospital from March 2018 to June 2024 were randomly divided into a control group(n=40)and a combined group(n=41)using a random number table.Both groups received dental pulp revascularization.After root canal disinfection,the control group received calcium hydroxide paste for cavity sealing,while the combined group additionally received CGF based on the control group.Clinical efficacy,bite force,root length,canal wall thickness,pain,and adverse reactions were compared between the two groups.Results At 12 months after surgery,the total effective rate of the combined group(95.12%)was higher than that of the control group(77.50%)(P<0.05).The bite force,root length,and canal wall thickness of both groups were significantly higher than before treatment,and the combined group showed higher levels than the control group(P<0.05).At 3,6,9,and 12 months after treatment,the visual analogue scale(VAS)scores in both groups were lower than before treatment,and there was no significant difference between the two groups at these time points(P>0.05).During postoperative follow-up,the overall incidence of adverse reactions,including apical inflammation,root canal calcification,and tooth discoloration,did not differ significantly between the two groups(P>0.05).Conclusion The combination of calcium hydroxide paste and CGF in treating young permanent teeth with pulpitis and pulp necrosis can effectively promote root growth,increase canal wall thickness,enhance bite force,and does not increase adverse reactions,showing significant clinical efficacy.
作者
杨丽丽
徐志媛
李翠梅
时炳正
于嘉昂
Yang Lili;Xu Zhiyuan;Li Cuimei;Shi Bingzheng;Yu Jiaang(Department of Dentistry,Stomatology Branch,Cangzhou People's Hospital,Cangzhou 061000)
出处
《口腔材料器械杂志》
2025年第4期236-241,共6页
Chinese Journal of Dental Materials and Devices
基金
河北省沧州市重点研发计划指导项目(222106002)。
关键词
氢氧化钙糊剂
浓缩生长因子
年轻恒牙血运重建
临床效果
Calcium hydroxide paste
Concentrated growth factor
Young permanent tooth revascularization
Clinical efficacy
