摘要
目的:探究D-二聚体(D-D)、平均血小板体积(MPV)及红细胞分布宽度(RDW)在妊娠糖尿病(GDM)预后评估中的临床意义。方法:选择于广州白云山医院2022年1月—2024年12月产检并分娩的99例GDM患者为研究对象,按照妊娠结局分为良好组(62例)及不良组(37例)。比较两组D-D、MPV、RDW水平。评估D-D、MPV、RDW单一及联合检测对GDM患者不良妊娠结局的预测效能。结果:GDM组D-D、MPV、RDW水平均高于对照组(P<0.05)。受试者工作特征曲线分析显示,D-D、MPV、RDW三项指标联合评估不良妊娠结局的效能最高(曲线下面积=0.879,P<0.001)。结论:妊娠结局不良的GDM患者D-D、MPV、RDW水平高于妊娠结局良好者,三指标联合预测GDM预后情况的效能最高。
Objective:To explore the clinical significance of D-dimer(D-D),mean platelet volume(MPV),and red blood cell distribution width(RDW)in the prognosis assessment of gestational diabetes mellitus(GDM).Methods:A total of 99 patients with gestational diabetes mellitus(GDM)who underwent prenatal examination and delivered at Guangzhou Baiyunshan Hospital from January 2022 to December 2024 were selected as the research subjects and divided into the good group(62 cases)and the poor group(37 cases)according to the pregnancy outcome.The levels of D-D,MPV and RDW between the two groups were compared to evaluate the predictive efficacy of single and combined detection of D-D,MPV and RDW for adverse pregnancy outcomes in patients with GDM.Results:The levels of D-D,MPV and RDW in the GDM group were all higher than those in the control group(P<0.05).Receiver operating characteristic curve analysis showed that the combined assessment of adverse pregnancy outcomes by the three indicators of D-D,MPV,and RDW had the highest efficacy(area under the curve=0.879,P<0.001).Conclusion:The levels of D-D,MPV and RDW in GDM patients with poor pregnancy outcomes are higher than those in patients with good pregnancy outcomes.The combined prediction of the three indicators has the highest efficacy in predicting the prognosis of GDM.
作者
余文凤
Yu Wenfeng(Department of Laboratory Medicine,Guangzhou Baiyunshan Hospital,Guangzhou 510515,Guangdong Province,China)
出处
《中外医药研究》
2025年第29期151-153,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
