摘要
本团队20多年来致力于开展南药化橘红资源的开发与利用,建立了化橘红psbA-trnH区、ITS区和ISSRPCR的分子指纹图谱;明确了化橘红真正发挥药效的物质基础(化学物质基础、药效物质基础);系统阐明了化橘红的作用机制,深入挖掘其作用本质;完善了化橘红质量评价体系,推动了化橘红的国际化进程;开发以化橘红为基源的创新药物,延长了化橘红的产业链,对促进乡村振兴起到了重要作用。
For more than 20 years,our team has been committed to the development and utilization on the resources of Exocarpium Citri Grandis,and established the molecular fingerprints of psbA-trnH region,ITS region and ISSR-PCR of Exocarpium Citri Grandis.The chemical material basis and drug effect material basis of Exocarpium Citri Grandis have been demonstrated.The mechanisms of actions of Exocarpium Citri Grandis were systematically expounded.A reliable and effective quality evaluation system of Exocarpium Citri Grandis was developed,and thus the process of internationalization of Exocarpium Citri Grandis was significantly accelerated.In addition,some innovative drugs based on Exocarpium Citri Grandis have been researched and developed.These contributions together have greatly extend the industrial chain of Exocarpium Citri Grandis and played an important role in promoting rural revitalization.
作者
苏薇薇
李沛波
吴灏
彭维
苏畅
聂怡初
罗钰龙
李泮霖
SU Weiwei;LI Peibo;WU Hao;PENG Wei;SU Chang;NIE Yichu;LUO Yulong;LI Panlin(School of Life Sciences,Sun Yat-sen University,Guangzhou 510275,China)
基金
广东省基础与应用基础研究基金(2022A1515012228)
“十四五”广东省农业科技创新九大主攻方向专项(2023SDZG07)
广东省乡村振兴战略专项(2024KJ22)。
关键词
南药
化橘红
资源开发
southern medicine
Exocarpium Citri Grandis
resource development
