摘要
乳腺癌术后患侧上肢淋巴水肿(breast cancer-related lymphedema,BCRL)是乳腺癌相关腋窝淋巴结清扫术后的常见并发症,其发病机制与腋窝淋巴引流系统破坏密切相关。本文系统综述BCRL的预防策略(包括腋窝手术降阶梯、非手术干预及预防性显微外科技术)和治疗手段(非手术综合消肿疗法、淋巴引流通路重建术及减容手术),结合最新循证医学证据,探讨当前临床实践中的争议点及未来研究方向,旨在为BCRL的规范化管理提供参考。
Breast cancer-related lymphedema(BCRL)is a common and severe complication of axillary lymph node dissection,with its pathogenesis closely linked to the disruption of axillary lymphatic drainage.This article systematically reviews the preventive strategies for BCRL(de-escalation of axillary surgery,non-surgical interventions,and prophylactic microsurgical techniques),along with treatment modalities(non-surgical complex decongestive therapy,lymphatic reconstruction surgery,and debulking procedures).Current clinical controversies and future research directions have also been discussed,by integrating the latest evidence-based medical data,to provide a reference for standardized BCRL management.
作者
陈翱翔
赵洪猛
曹旭晨
王欣
Aoxiang Chen;Hongmeng Zhao;Xuchen Cao;Xin Wang(First Department of Breast Surgery,Tianjin Medical University Cancer Institute&Hospital,National Clinical Research Center for Cancer,Tianjin Key Laboratory of Cancer Prevention and Therapy,Tianjin’s Clinical Research Center for Cancer,Key Laboratory of Breast Cancer Prevention and Therapy(Ministry of Education),Tianjin 300060,China)
出处
《中国肿瘤临床》
北大核心
2025年第18期940-943,共4页
Chinese Journal of Clinical Oncology
基金
天津市重点医学学科(专科)建设项目(编号:TJYXZDXK-009A)资助。
关键词
乳腺癌
淋巴水肿
预防
保守治疗
手术治疗
breast cancer
Iymphedema
prevention
conservative treatment
surgical treatment
