摘要
非黑色素瘤皮肤癌(non-melanoma skin cancer,NMSC)是世界范围内常见的恶性肿瘤,由于人口老龄化以及紫外线暴露其发病率正逐年上升。基底细胞癌(basal cell carcinoma,BCC)和皮肤鳞状细胞癌(cutaneous squamous cell carcinoma,CSCC)是最常见的类型,虽然手术是这两种肿瘤治疗的金标准,但对于晚期或已转移的NMSC,靶向治疗及免疫治疗成为新的希望。该综述主要阐述常见NMSC的新兴治疗进展及相关机制,以期为晚期及转移性NMSC治疗提供参考。
Non-melanoma skin cancer(NMSC)is a common malignancy worldwide,and its incidence is increasing every year due to the aging population and exposure to ultraviolet light.Basal cell carcinoma(BCC)and cutaneous squamous cell carcinoma(CSCC)are the most common types,and although surgery is the gold standard for the treatment of these two tumors,targeted therapy and immunotherapy have become the new hope for advanced or metastatic NMSC.This review mainly elaborates on the emerging therapeutic advances and related mechanisms of common NMSC,in order to provide a reference for the treatment of advanced and metastatic NMSC.
作者
穆亚楠
陈星会
何璐
张逸
李东霞
MU Yanan;CHEN Xinghui;HE Lu;ZHANG Yi;LI Dongxia(Department of Dermatology,Affiliated Hospital of Inner Mongolia Medical University,Inner Mongolia Hohhot 010050,China)
出处
《现代肿瘤医学》
2026年第1期139-145,共7页
Journal of Modern Oncology
基金
内蒙古自治区自然科学基金项目(编号:2023QN08039)
内蒙古自治区高等学校科学研究项目(编号:NJZY23126)。
关键词
非黑色素瘤皮肤癌
基底细胞癌
皮肤鳞状细胞癌
靶向治疗
免疫治疗
non-melanoma skin cancer
basal cell carcinoma
cutaneous squamous cell carcinoma
targeted therapy
immunotherapy
