摘要
AIM:To evaluate whether fluid-air exchange is an effective treatment for unclosed macular hole(MH)after primary vitrectomy.METHODS:This retrospective study included patients with an unclosed MH within 1–2wk after vitrectomy.Patients were divided into the vitrectomy,fluid-air exchange,and observation groups according to the secondary treatment.The anatomical outcomes and postoperative visual acuity were recorded.RESULTS:The analysis included 25 eyes in 25 patients(16 females)aged 37–74y(vitrectomy group,n=10;fluid-air exchange group,n=9;observation group,n=6).Closure rate after secondary treatment was 100%in the vitrectomy group,88.9%in the fluid-air exchange group and 33.3%in the observation group.Optical coherence tomography images obtained at the last follow-up revealed that continuity of the external limiting membrane(ELM)was significantly more common(P=0.004)in the fluid-air group(8/9 eyes,88.9%)than in the vitrectomy group(2/10 eyes,20.0%)and that macular morphology was better in the fluid-air group than in the vitrectomy group.No serious complications were observed after secondary treatment.CONCLUSION:Fluid-air exchange is an alternative option to repeat vitrectomy for patients with an unclosed MH after initial vitrectomy with elevated macular edge.
