摘要
目的:观察五联一体综合康复在脑梗死患者康复治疗中的应用效果。方法:选取2021年6月—2023年1月南阳市第一人民医院收治的100例脑梗死患者作为研究对象,应用电脑随机分组法生成随机序列,并进行分配隐藏后,将其分别列为常规组和五联组,每组各50例。常规组患者接受常规康复治疗,五联组患者接受五联一体综合康复治疗,治疗结束后均随访1年。比较两组患者的神经功能、认知功能、肢体运动功能及预后情况。结果:治疗后,五联组患者的神经元特异性烯醇化酶(NSE)、中枢神经特异蛋白(S100β)、神经肽Y(NPY)、神经功能缺损量表(NIHSS)评分均低于常规组,差异均有统计学意义(t=2.887、3.420、3.958、3.073,P<0.05);随访第6个月、第12个月时,五联组患者简易精神状态量表(MMSE)评分、蒙特利尔认知评估量表(MoCA)评分均高于常规组,差异均有统计学意义(t=3.025、2.949、2.984、2.696,P<0.05);随访第6个月、第12个月时,五联组患者的简化Fugl-Meyer运动功能评定量表上肢(FMA-UL)评分、下肢(FMA-LL)评分均高于常规组,差异均有统计学意义(t=2.413、2.399、2.682、2.957,P<0.05);五联组患者的不良预后发生率低于常规组,差异有统计学意义(χ2=7.162,P<0.05)。结论:五联一体综合康复能改善脑梗死患者的神经功能及认知功能,在恢复患者肢体功能的同时可有效降低不良预后发生风险。
Objective:To observe the application effect of the five in one comprehensive rehabilitation in the rehabilitation treatment of patients with cerebral infarction.Methods:Based on computer random grouping method,100 patients with cerebral infarction admitted to the First People’s Hospital of Nanyang from June 2021 to January 2023 were selected as the research object,and divided into a conventional group and a five in one group,with 50 cases in each group.The conventional group received routine rehabilitation treatment,while the five in one group received five in one comprehensive rehabilitation treatment.After treatment,patients in both groups were followed up for one year to compare their neurological function,cognitive function,limb motor function,and prognosis.Result:The scores of neuron-specific enolase(NSE),central nervous system-specific protein(S100β),neuropeptide Y(NPY)and Neurological Deficit Scale(NIHSS)in pentagentine group were lower than those in conventional group,,and the difference was statistically significant(t=2.887,3.420,3.958,3.073;P<0.05).The scores of minimum mental state examination(MMSE)and Montreal cognitive assessment(MoCA)in the five in one group were higher than those in the conventional group at the 6th and 12th months of follow-up,and the difference was statistically significant(t=3.025,2.949,2.984,2.696;P<0.05).The Fugl-Meyer assessment upper limbs(FMA-UL)and Fugl-Meyer assessment lower limbs(FMA-LL)scores of the five-group were higher than those of the conventional group at 6 and 12 months of follow-up,and the difference was statistically significant(t=2.413,2.399,2.682,2.957;P<0.05).The incidence of adverse prognosis in the quintuple group was lower than that in the conventional group,and the difference was statistically significant(χ2=7.162;P<0.05).Conclusion:The five in one comprehensive rehabilitation could improve the neurological and cognitive functions of patients with cerebral infarction,and has a positive significance in promoting limb function recovery and reducing the risk of adverse prognosis.
作者
史明磊
朱虹
Shi Minglei;Zhu Hong(Department of NeurologyⅡ,The First People’s Hospital of Nanyang,Nanyang,Henan,473000,China)
出处
《黑龙江医学》
2025年第21期2618-2621,共4页
Heilongjiang Medical Journal
关键词
脑梗死
康复治疗
五联一体综合康复
神经功能
预后情况
Cerebral infarction
Rehabilitation therapy
Five in one comprehensive rehabilitation
Neurological function
Prognostic situation
