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对粘连性肠梗阻实施腹腔镜肠粘连松解术治疗的临床效果研究

Study on the Clinical Effect of Laparoscopic Intestinal Adhesiolysis in the Treatment of Adhesive Intestinal Obstruction
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摘要 探讨对粘连性肠梗阻患者实施腹腔镜肠粘连松解术治疗的临床效果。选取2024年1月—2025年1月于南通市第一人民医院接受手术治疗的80例粘连性肠梗阻患者作为研究对象,按手术方法的差异将其分为对照组和观察组,每组各40例。对照组采用传统开腹手术,观察组采用腹腔镜肠粘连松解术。对比两组患者的手术指标、并发症发生情况、肠道功能、炎症因子水平、肠道屏障功能和生活质量。结果显示,与对照组比较,观察组术后排气时间、术后排便时间及住院时间更短,术中出血量更少,并发症发生率显著更低(P<0.05);术后1周及术后3个月,观察组MTL、GAS及VIP高于对照组,CRP、IL-6、DAO、D-乳酸低于对照组,生活质量高于对照组(P<0.05)。研究发现,在粘连性肠梗阻的治疗中,腹腔镜肠粘连松解术的应用能够缩短手术时间,降低出血量,且并发症发生率低,有助于促进患者肠道功能恢复,提高其生活质量,可推广。 This study explores the clinical effect of laparoscopic intestinal adhesiolysis in the treatment of patients with adhesive intestinal obstruction.A total of 80 patients with adhesive intestinal obstruction who underwent surgical treatment at Nantong First People’s Hospital from January 2024 to January 2025 were selected as research subjects.They were divided into the control group and the observation group according to the difference in surgical methods,with 40 cases in each group.The control group received traditional open surgery,while the observation group received laparoscopic intestinal adhesiolysis.The surgical indicators,incidence of complications,intestinal function,levels of inflammatory factors,intestinal barrier function,and quality of life were compared between the two groups.The results showed that:Compared with the control group,the observation group had shorter postoperative exhaust time,postoperative defecation time,and hospital stay,less intraoperative blood loss,and a significantly lower incidence of complications(P<0.05);At 1 week and 3 months after surgery,the levels of motilin(MTL),gastrin(GAS),and vasoactive intestinal peptide(VIP)in the observation group were higher than those in the control group;the levels of C-reactive protein(CRP),interleukin-6(IL-6),diamine oxidase(DAO),and D-lactic acid were lower than those in the control group;and the quality of life was higher than that in the control group(P<0.05).The study concludes that in the treatment of adhesive intestinal obstruction,the application of laparoscopic intestinal adhesiolysis can shorten the surgical recovery process,reduce blood loss,and lower the incidence of complications.It also helps promote the recovery of patients’intestinal function and improve their quality of life,which is worthy of clinical promotion.
作者 杨逸凡 YANG Yifan(Nantong First People’s Hospital,Nantong,Jiangsu 226000)
出处 《科技与健康》 2025年第19期41-44,共4页 Technology and Health
关键词 粘连性肠梗阻 腹腔镜肠粘连松解术 肠道功能 并发症 生活质量 adhesive intestinal obstruction laparoscopic intestinal adhesiolysis intestinal function complications quality of life
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