摘要
综述了厚朴酚[从厚朴(Magnolia officinalis)中提取的酚类化合物]在抗病原微生物、抗炎、抗氧化、抗肿瘤、神经保护、肠胃功能调节、心血管保护以及脂质代谢调节等方面的研究进展,总结了相关试验结果与数据,并针对当前研究中存在的机制不清、临床验证不足等问题,提出未来应加强分子机制和临床转化等研究方向。
The research progress on magnolol(a phenolic compound extracted from Magnolia officinalis)was reviewed,focusing on its pharmacological action such as anti-pathogenic,anti-inflammatory,antioxidant,and anti-tumor activities,along with neuroprotec-tive,gastrointestinal regulatory,cardiovascular protective,and lipid metabolism regulatory properties.Relevant experimental results and data were summarized.Given the limitations of current studies,including unclear mechanisms and insufficient clinical validation,it was suggested that future research should prioritize elucidating molecular mechanisms and advancing clinical translation.
作者
郭耀东
孙施蕊
刘甜钰
刘思思
张晓文
贾国伦
Hassan Idris Abdu
GUO Yao-dong;SUN Shi-rui;LIU Tian-yu;LIU Si-si;ZHANG Xiao-wen;JIA Guo-lun;HASSAN Idris Abdu(College of Health Management,Shangluo University/Shaanxi Union Research Center of University and Enterprise for Health and Wellness Industry/Shangluo Health and Wellness Industry Research Institute,Shangluo 726000,Shaanxi,China)
出处
《湖北农业科学》
2025年第10期140-146,共7页
Hubei Agricultural Sciences
基金
陕西省重点研发计划项目(2020NY-111)
陕西秦岭特色生物资源产业技术研究院有限公司开放基金项目(23HKY039)
2024年陕西省大学生创新创业训练计划项目(S202411396067)
商洛市秦岭康养产业科技创新平台建设项目(2023-C-0012)。
关键词
厚朴酚
药理作用
研究进展
作用机制
临床应用
活性成分
magnolol
pharmacological action
research progress
mechanism of action
clinical application
active ingredient
