摘要
目的:观察脑梗死疾病早期诊断中灌注加权成像(PWI)的应用方法与临床效果。方法:将120例脑梗死患者纳入本次研究,均来源于2022年12月~2023年12月本院收治的患者。按照疾病情况分为超急性组(n=15)、急性期组(n=55)、亚急性期组(n=30)、慢性期组(n=20),对患者开展PWI诊断,统计各组健侧与梗死区脑组织区域相关表观弥散系数(ADC)值,比较各组两侧脑组织PWI参数,包括脑血容量(CBV)、脑血流量(CBF)、平均通过时间(MTT)、达峰时间(TTP),分别统计正常、降低、延长病例数。结果:比较各组健侧与梗死区脑组织区域相关ADC值差异,检验显示差异均有统计学意义(P<0.05)。统计并比较各组两侧脑组织PWI参数,处于超急性期的患者在CBV、CBF方面大部分表现出下降,MTT和TTP大部分表现出延长;处于急性期的患者在CBV方面大多表现为降低,其次为正常,表现为延长的相对较少,在CBF方面,患者多表现为降低,其次为延长,表现为正常的较少,在TTP方面,表现为延长的最多,其次为降低,表现为集中的最少,在MTT方面,表现为延长的最多,其次为降低,表现为集中的最少;处于亚急性的患者在CBV方面大多表现为正常,其次为降低,未出现延长病例。在CBF方面,大多表现为正常,其次为降低,未出现延长病例。在TTP方面,大多表现为延长,其次为降低,未出现正常病例,在MTT方面,大多表现为延长(76.67%),其次为降低,未出现正常病例;处于慢性期的患者在CBV、CBF方面均表现出降低,在TTP方面,大多表现为降低,其次为延长,未出现正常病例,在MTT方面,大多表现为降低,其次为延长,未出现正常病例。结论:脑梗死疾病早期诊断中PWI技术的应用可以获得理想的诊断效果。
Objective:To observe the application method and clinical effect of perfusion weighted imaging(PWI)in the early diagnosis of cerebral infarction.Methods:120 patients with cerebral infarction were included in this study,all of whom were admitted to our hospital from December 2022 to December 2023.According to the disease condition,patients were divided into hyperacute group(n=15),acute phase group(n=55),subacute phase group(n=30),and chronic phase group(n=20).PWI diagnosis was performed on patients,and the apparent diffusion coefficient(ADC)values related to the healthy and infarcted brain tissue regions were calculated in each group.The PWI parameters of the brain tissue on both sides of each group were compared,including cerebral blood volume(CBV),cerebral blood flow(CBF),mean transit time(MTT),and time to peak(TTP),and the number of normal,decreased,and prolonged cases were counted,respectively.Results:Comparing the differences in ADC values between the healthy and infarcted brain tissue regions in each group,the test showed that the differences were statistically significant(P<0.05).By statistically comparing the PWI parameters of brain tissues on both sides of each group,it can be concluded that patients in the hyperacute phase mostly exhibit a decrease in CBV and CBF,while MTT and TTP are mostly prolonged;Patients in the acute phase mostly show a decrease in CBV,followed by normal,with relatively less elongation.In CBF,patients tend to show a decrease,followed by elongation,with fewer normal manifestations.In TTP,it shows the most elongation,followed by a decrease,with the least concentration.In MTT,it shows the most elongation,followed by a decrease,with the least concentration;Most patients in subacute condition show normal CBV,followed by decreased CBV,with no cases of prolonged CBV.In terms of CBF,most cases are normal,followed by a decrease,and no cases of prolongation have been observed.In terms of TTP,it is mostly manifested as prolongation,followed by decrease,and no normal cases have been observed.In terms of MTT,it is mostly manifested as prolongation(76.67%),followed by decrease,and no normal cases have been observed;Patients in the chronic phase show a decrease in both CBV and CBF.In terms of TTP,most cases show a decrease,followed by prolongation,and no normal cases have been observed.In terms of MTT,most cases show a decrease,followed by prolongation,and no normal cases have been observed.Conclusion:The application of PWI technology in the early diagnosis of cerebral infarction can achieve ideal diagnostic results.
作者
尹莹霞
陈建
刘小涛
黄云
YIN Ying-xia;CHEN Jian;LIU Xiao-tao;HUANG Yun(Ji’an Central People’s Hospital,Jiangxi Ji’an 343000)
出处
《中国医疗器械信息》
2025年第19期81-83,155,共4页
China Medical Device Information
关键词
脑梗死
功能磁共振技术
灌注加权成像
诊断
cerebral infarction
functional magnetic resonance imaging technology
perfusion weighted imaging
diagnosis
