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6~15岁儿童腭中缝密度比率变化规律研究

Research on the variation pattern of midpalatal suture density ratio in children aged 6 to 15 years old
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摘要 目的研究6~15岁不同年龄和性别儿童腭中缝密度比率变化规律,为临床诊断和扩弓矫治时机的选择提供参考依据。方法收集2023年1—12月于四川大学华西口腔医院儿童口腔科早期矫治专科就诊的164例6~15岁患儿的临床和影像学资料行回顾性研究。患儿锥形束CT数据用Dolphin Imaging软件进行上颌复合体的三维模型重建,滤除软组织获取腭部图像,应用ImageJ软件测量腭中缝灰度值及两侧腭部平均灰度值,其比值记为腭中缝密度比率,比较不同年龄和性别患儿腭中缝密度比率差异。结果男性患儿腭中缝密度比率与年龄的最佳回归曲线为四次方回归曲线(R^(2)=0.606,P<0.001),女性为五次方回归曲线(R^(2)=0.591,P<0.001)。腭中缝密度比率变化趋势可分为平缓期、下降期及上升期,对应男性患儿年龄段依次为6~10、>10~13、>13~15岁,其腭中缝密度比率依次为0.629±0.065、0.510±0.078、0.535±0.042,除下降期与上升期比较外,其他时期腭中缝密度比率两两比较,差异均有统计学意义(均P<0.05);对应女性患儿年龄段依次为6~9、>9~12、>12~15岁,其腭中缝密度比率依次为0.593±0.062、0.491±0.075、0.554±0.061,各期腭中缝密度比率两两比较,差异均有统计学意义(均P<0.05)。对6~15岁患儿平均划分为5个年龄段,其中>7~9、>9~11、>13~15岁年龄段不同性别患儿腭中缝密度比率比较,差异均有统计学意义(均P<0.05);6~7、>11~13岁年龄段不同性别患儿腭中缝密度比率比较,差异均无统计学意义(均P>0.05)。结论不同性别儿童腭中缝发育进程存在差异,女性腭中缝密度比率与年龄的回归曲线变化时间点较男性早约1年;结合研究结果与临床经验,男性7~10岁,女性7~9岁可能为上颌扩弓矫治的较佳时机,为临床个性化矫治方案的制定提供一定参考。 Objective To study the variety patterns of the midpalatal suture density ratio in children of different ages(6 to 15 years old)and genders to provide reference for clinical diagnosis and the timing of palatal expansion treatment.Methods The clinical and imaging data of 164 children aged 6 to 15 years old who visited the West China Hospital of Stomatology from January to December 2023 were collected and analyzed retrospectively.The three-dimensional model of the maxillary complex was reconstructed using Dolphin Imaging software based on cone beam CT data of children.Soft tissue was filtered out to obtain palatal images.ImageJ software was used to measure the grey density of the middle palatal suture and the average grey density of both sides of the palate.The ratio was recorded as the midpalatal suture density ratio,and the differences in the midpalatal suture density ratio in children of different ages and genders were compared.Results The best regression curve between the midpalatal suture density ratio and age was a fourth power regression curve in male children(R^(2)=0.606,P<0.001),and a fifth power regression curve in female children(R^(2)=0.591,P<0.001).The change trend of the midpalatal suture density ratio could be divided into flat,declining and rising periods,the corresponding age groups of male children were 6-10 years old,>10-13,and>13-15 years old,and the midpalatal suture density ratio was 0.629±0.065,0.510±0.078,and 0.535±0.042.Except for the comparison between the declining and rising periods,the comparisons of midpalatal suture density ratio between each two of other periods showed statistically significant differences(P<0.05 for all);the corresponding age groups of female children were 6-9,>9-12,and>12-15 years old,and the midpalatal suture density ratio were 0.593±0.062,0.491±0.075,and 0.554±0.061.There were statistical differences in the midpalatal suture density ratio between each two periods(P<0.05 for all).Children aged 6-15 were divided into 5 age groups on average.Among them,there were statistically significant differences in the midpalatal suture density ratio in children aged>7-9,>9-11,and>13-15 between different genders(P<0.05 for all);there were no statistically significant differences in the midpalatal suture density ratio in children aged 6-7 and>11-13 between different genders(P>0.05 for all).Conclusion There are differences in the development process of the midpalatal suture in children between different genders.The time point of the change in regression curve between the midpalatal suture density ratio and age in the female is about 1 year earlier than that in the male.Based on the research results and clinical experience,the periods of 7-10 years old in the male and 7-9 years old in the female may be a better opportunity for maxillary expansion,which provides some reference for the formulation of clinical personalized correction plans.
作者 马玗玟 曾维佳 余幸 李小兵 MA Yuwen;ZENG Wei-jia;YU Xing;LI Xiao-bing(State Key Laboratory of Oral Diseases,National Center for Stomatology,National Clinical Research Center for Oral Diseases,Department of Pediatric Dentistry,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China)
出处 《中国实用口腔科杂志》 2025年第5期578-584,共7页 Chinese Journal of Practical Stomatology
基金 四川省科技计划项目(2022YFG0203)。
关键词 锥形束CT 上颌扩弓矫治 腭中缝密度比率 腭中缝成熟程度 cone beam CT maxillary expansion treatment midpalatal suture density ratio midpalatal suture maturation
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