摘要
目的:探究角膜塑形镜对青少年近视患者角膜功能、视力恢复的影响。方法:回顾性分析2021年7月—2024年1月于厦门大学附属第一医院行视力检查及矫正的120例青少年近视患者(186眼)资料,基于矫正方式不同将其分为对照组(佩戴常规近视眼镜,59例91眼)、塑形镜组(持续戴角膜塑形镜6个月,61例95眼)。于戴镜前、戴镜后1周、1个月、3个月、6个月进行角膜功能和视力检查,比较两组角膜内皮细胞数、角膜屈光度、眼压长度、眼轴、角膜厚度、前后表面高阶像差、裸眼视力(UCVA)。结果:戴镜后1周、1个月、3个月、6个月两组角膜屈光度、眼轴长度、角膜厚度均明显降低,塑形镜组各时点屈光度高于对照组,眼轴长度、角膜厚度低于对照组,差异有统计学意义(P<0.05)。戴镜后1周、1个月、3个月、6个月两组前表面高阶像差均高于戴镜前,且塑形镜组各时点前表面高阶像差均高于对照组,差异有统计学意义(P<0.05)。戴镜后1周、1个月、3个月、6个月塑形镜组UCVA(logMA)均优于对照组,差异有统计学意义(P<0.05)。Pearson参数相关性分析显示,近视患者戴镜后6个月角膜屈光度、角膜厚度、眼轴长度与裸眼远视力(UDVA)呈正相关,前表面高阶像差与UDVA呈负相关(P<0.05)。结论:青少年近视患者角膜塑形镜后1周角膜功能和视力恢复最为明显,而持续佩戴角膜塑形镜6个月可有效改善患者角膜功能及裸眼视力。
Objective:To investigate the effect of keratoplasty on corneal function and visual acuity recovery in adolescent myopic patients.Method:The data of 120 adolescent myopia patients(186 eyes)who underwent visual acuity examination and correction at the First Affiliated Hospital of Xiamen University from July 2021 to January 2024 were retrospectively analyzed,and based on the different correction methods,they were divided into the control group(59 cases and 91 eyes wearing conventional myopia spectacles),and the plasmapheresis group(61 cases and 95 eyes wearing keratoplasty lenses continuously for 6 months).Corneal function and visual acuity were examined before,1 week,1 month,3 months,and 6 months after lens wear and the number of corneal endothelial cells,corneal refractive error,intraocular pressure length,ocular axis,corneal thickness,anterior and posterior surface high-order aberration,and naked-eye visual acuity(UCVA)were compared between the two groups.Result:Corneal refraction,axial length,and corneal thickness were significantly reduced in both groups at 1 week,1 month,3 months,and 6 months after wearing the lenses,and the refraction was higher in the plastic lens group than in the control group at all time points,and the axial length and corneal thickness were lower than those in the control group,and the difference was statistically significant(P<0.05).The anterior surface high-order aberration was higher than that before lens wear in both groups at 1 week,1 month,3 months,and 6 months after lens wear,and the anterior surface high-order aberration was higher in the plastigraphy group than that in the control group at all time points,and the difference was statistically significant(P<0.05).The UCVA(logMA)of the plastic lens group was better than that of the control group at 1 week,1 month,3 months,and 6 months after lens wear,and the difference was statistically significant(P<0.05).Pearson's parametric correlation analysis showed that corneal refraction,corneal thickness,and ocular axis length were positively correlated with naked-eye distance visual acuity(UDVA),and anterior surface higher-order aberrations were negatively correlated with UDVA in myopia patients at 6 months after lens wear(P<0.05).Conclusion:The recovery of corneal function and visual acuity is most obvious 1 week after keratoplasty in adolescent myopic patients,while continuous wearing of keratoplasty lenses for 6 months can effectively improve patients'corneal function and naked-eye visual acuity.
作者
张东渝
方颉
任凤英
吕红丽
ZHANG Dongyu;FANG Jie;REN Fengying;LÜ Hongli(The First Affiliated Hospital of Xiamen University,Xiamen 361000,China;不详)
出处
《中外医学研究》
2025年第27期71-75,共5页
CHINESE AND FOREIGN MEDICAL RESEARCH
基金
厦门市医疗卫生指导性项目(3502Z20224ZD1204)。
关键词
近视
青少年
角膜塑形镜
角膜功能
视力恢复
Myopia
Juvenile
Orthokeratology lens
Corneal function
Vision recovery
