摘要
目的观察中药洗浴联合穴位按摩配合蓝光照射治疗新生儿病理性黄疸的临床疗效。方法选取2021年1月—2022年12月张家港市中医医院收治的新生儿病理性黄疸患者102例,采用区组随机法随机分为对照组和研究组,每组各51例。对照组给予常规治疗,研究组在对照组治疗的基础上给予中药洗浴联合穴位按摩治疗。治疗7 d后,观察比较两组患儿临床指标、临床疗效、黄疸指数及不良反应情况,治疗前后胆红素[总胆红素(Total bilirubin,TBIL)、直接胆红素(Direct bilirubin,DBIL)]水平、免疫功能指标[免疫球蛋白A(Immunoglobulin A,IgA)、免疫球蛋白G(Immunoglobulin G,IgG)、免疫球蛋白M(Immunoglobulin M,IgM)]。结果治疗后研究组排便次数较对照组明显增加,研究组胎便转黄时间、退黄时间、入住NICU的时间以及总住院时间均较对照组明显缩短,差异有统计学意义(P<0.05)。治疗后两组患儿TBIL、DBIL水平较治疗前降低,差异有统计学意义(P<0.05);且研究组TBIL、DBIL水平低于对照组,差异有统计学意义(P<0.05)。治疗后两组患儿IgA、IgG、IgM较治疗前升高,差异有统计学意义(P<0.05);且研究组IgA、IgG、IgM高于对照组,差异有统计学意义(P<0.05)。治疗第3、5、7天后研究组黄疸指数均明显低于对照组,差异有统计学意义(P<0.05)。治疗后研究组临床总有效率98.04%(50/51)明显高于对照组86.27%(44/51),差异有统计学意义(P<0.05)。治疗期间,研究组不良反应率3.92%(2/51)低于对照组17.65%(9/51),差异有统计学意义(P<0.05)。结论药洗浴联合穴位按摩治疗新生儿病理性黄疸,能够促进排便,降低胆红素水平,提高免疫功能和临床治疗疗效,减少不良反应,促进患儿更早康复。
Objective To explore the clinical efficacy of traditional Chinese medicine(TCM)bath combined with acupoint massage and blue light irradiation on neonatal pathological jaundice.Methods A total of 102 neonatal patients with pathological jaundice treated at Zhangjiagang Hospital of Traditional Chinese Medicine from January 2021 to December 2022 were selected and divided into a control group and a study group by the block randomization method,with 51 cases in each group.Both groups were given conventional treatment,while the study group additionally received a TCM bath combined with acupoint massage.Both groups were treated for 7 days.After treatment,clinical efficacy,clinical indicators,jaundice index,and adverse reaction were compared between the two groups,as well as the following items before and after treatment:bilirubin[total bilirubin(TBIL)and direct bilirubin(DBIL)],as well as immune function indicators[immunoglobulin A(IgA),immunoglobulin G(IgG),and immunoglobulin M(IgM)].Results After treatment,the defecation frequency in the study group was significantly more than that in the control group.The time of fetal stool turning yellow,yellow retreating,admission to the NICU,and the total hospital stay in the study group were all significantly shorter than those in the control group(P<0.05).The TBIL and DBIL levels were decreased in the two groups(P<0.05),with both levels being significantly lower in the study group(P<0.05).The IgA,IgG,and IgM levels were increased in both groups(P<0.05),with the three levels being significantly higher in the study group(P<0.05).On the 3rd,5th,and 7th days of treatment,the jaundice index of the study group was significantly lower than that of the control group(P<0.05).The total clinical effective rate of the study group was 98.04%(50/51),which was significantly higher than that of the control group(86.27%,44/51)(P<0.05).The adverse reaction rate in the study group was 3.92%(2/51),which was lower than 17.65%(9/51)in the control group(P<0.05).Conclusion In treating neonatal pathological jaundice,medicine TCM bath combined with acupoint massage can promote defecation,reduce bilirubin level,improve immune function and clinical efficacy,and reduce adverse reactions,promoting early recovery.
作者
马晓伟
蔡娟
MA Xiao-wei;CAI Juan(Department of Neonatology,Zhangjiagang Hospital of Traditional Chinese Medicine,Zhangjiagang Jiangsu 215600)
出处
《世界中西医结合杂志》
2025年第8期1662-1666,共5页
World Journal of Integrated Traditional and Western Medicine
基金
张家港市卫计系统青年科技项目(ZJGQNKJ201821)。
关键词
中药洗浴
穴位按摩
新生儿病理性黄疸
胆红素
黄疸指数
Traditional Chinese Medicine Bath
Acupoint Massage
Neonatal Pathological Jaundice
Bilirubin
Jaundice Index
