摘要
本研究提出了甲状腺疾病热消融治疗的“两段论”理论模型,揭示其在临床实践中的重要价值。该理论将热消融治疗分为两个阶段:治疗干预阶段和清除吸收阶段。治疗干预阶段以消融疗效为核心,通过术中即时评估的消融体积比(AVR)衡量疗效;清除吸收阶段关注术后坏死组织的免疫清除过程,通过较长时间内反复评估的消融区体积缩小率(VRR)反映吸收进程。此外,研究引入了消融前即刻病灶体积(V_(0))和术后即刻消融区初始体积(V_(1))两个核心概念,构建并优化了AVR和VRR的计算方法。通过对两阶段的本质特征解析及传统计算方法错误成因的分析,建立了甲状腺热消融治疗的疗效评价体系与吸收预后评估逻辑。
This study proposes a"two-stage"theoretical model for the thermal ablation treatment of thyroid diseases,highlighting its significant value in clinical practice.This theory categorizes thermal ablation treatment into two distinct stages:the treatment intervention stage and the clearance and absorption stage.The treatment intervention stage centers on ablation efficacy,with efficacy quantified by the ablation volume ratio(AVR),which is assessed immediately during the procedure.The clearance and absorption stage focuses on the immune-mediated clearance of necrotic tissue post-operation,with the absorption process characterized by the volume reduction rate(VRR)of the ablation area,evaluated repeatedly over an extended period.Additionally,the study introduces two key concepts:the immediate lesion volume(V_(0))prior to ablation and the initial volume(V_(1))of the ablation area immediately following the operation.It further develops and optimizes calculation methods for AVR and VRR.By analyzing the essential characteristics of both stages and identifying errors in traditional calculation methods,the study establishes an efficacy evaluation system and an absorption prognosis evaluation framework for thyroid thermal ablation treatment.
作者
章建全
闫磊
程杰
陈红琼
宋家琳
Zhang Jianquan;Yan Lei;Cheng Jie;Chen Hongqiong;Song Jialin(Department of Interventional Ultrasound,Parkway Shanghai Hospital,Shanghai 201107,China;Department of Interventional Ultrasound,Shanghai International Medical Center,Shanghai 201318,China;Department of Ultrasound,Suzhou 100th Hospital,Suzhou 215007,China;Department of Ultrasound,Changzheng Hospital,Shanghai 200003,China)
出处
《中华超声影像学杂志》
北大核心
2025年第9期823-828,共6页
Chinese Journal of Ultrasonography
基金
国家自然科学基金(81171436)。
关键词
“两段论”理论
热消融治疗
甲状腺
消融体积比
体积缩小率
消融复合体
Two-stage theory
Thermal ablation therapy
Thyroid
Ablation volume ratio
Volume reduction ratio
Ablation complex
