摘要
目的提醒临床医生在使用多索茶碱时需密切关注用药安全。方法报告并分析多索茶碱致儿童过敏性休克1例,通过检索文献数据库,探讨多索茶碱致过敏性休克的机制和应对措施。结果本例患儿出现过敏性休克很可能是多索茶碱所致,该患儿耐受性差,增加了过敏性休克的发生风险;患儿长时间发热和临床经验性用药可能加剧儿童中毒风险。结论临床医师应严格掌握多索茶碱的适应证及使用剂量,警惕用药过程中出现的不良反应;药品监管部门应定期对药品说明书内容进行修订和补充。
Objective To remind the clinician to pay close attention to medication safety of doxofylline.Methods A case of anaphylactic shock induced by doxofylline in children was reported and analyzed.The mechanism and countermeasures of doxofylline induced anaphylactic shock were discussed by searching the literature database.Results This case of anaphylactic shock is likely induced by doxofylline.The child has poor tolerance,which increases the risk of anaphylactic shock;the child's prolonged fever and clinical empirical medication may exacerbate the risk of poisoning in children.Conclusion Clinicians should control the indications and dosage of doxofylline strictly,and be alert to the adverse reactions in the course of medication.The drug regulatory department shall revise and supplement the contents of drug instructions regularly.
作者
张祥芳
赵晓月
ZHANG Xiangfang;ZHAO Xiaoyue(Lanling Market Supervision Administration,Linyi 277700,China;不详)
出处
《中国处方药》
2025年第18期61-64,共4页
Journal of China Prescription Drug
