摘要
目的 研究肠内营养支持用于维持性血液透析(MHD)患者营养及骨骼肌质量的影响。方法 选取2022年1月—2023年12月在景德镇市第二人民医院行维持性血液透析患者92例作为研究对象,按照组间基线资料均衡可比的原则将患者分为观察组和对照组,每组46例。对照组实施常规饮食干预,观察组在常规饮食干预的基础上实施肠内营养干预。观察并比较两组患者于治疗第1天、治疗6个月后的营养状况、血清学指标及骨骼肌质量指数水平。结果 治疗第1天,两组患者的营养状况评分、血清白蛋白(ALB)、前清蛋白(PAB)、血尿素氮(BUN)、肌酐(Cr)、骨骼肌质量指数比较均无统计学意义(P>0.05)。治疗6个月后,观察组SGA评分高于对照组,差异有统计学意义(P<0.05)。治疗6个月后,观察组ALB、PAB均高于对照组,BUN、Cr水平低于对照组,差异均有统计学意义(P<0.05)。治疗6个月后,观察组患者骨骼肌质量指数高于对照组,差异有统计学意义(P<0.05)。结论 对维持性血液透析患者实施肠内营养支持后,患者营养水平和骨骼肌质量指数提高,肾功能得到改善。
Objective To study the effects of enteral nutrition support on nutrition status and skeletal muscle mass in maintenance hemodialysis(MHD)patients.Methods A total of 92 patients who underwent maintenance hemodialysis at the Second People's Hospital of Jingdezhen from January 2022 to December 2023 were selected as the study subjects.According to the principle of balanced and comparable baseline data between groups,the patients were divided into an observation group and a control group,with 46 cases in each group.The control group received routine dietary intervention,while the observation group received enteral nutrition intervention in addition to the routine dietary intervention.The nutritional status,serological indicators,and skeletal muscle mass index levels of both groups of patients were observed and compared on the first day of treatment and after 6 months of treatment.Results On thefirst day of treatment,there was no statistically significant difference in the nutritional status scores,albumin(ALB),prealbumin(PAB),blood urea nitrogen(BUN),creatinine(Cr),and skeletal muscle mass indices between the two groups(P>0.05).After 6 months of treatment,the SGA score of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).After 6 months of treatment,the ALB and PAB of the observation group were higher than those of the control group,while the BUN and Cr levels were lower than those in the control group,the differences were statistically significant(P<0.05).After 6 months of treatment,the skeletal muscle mass index of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion After implementing enteral nutrition support in maintenance hemodialysis patients,the patients'nutritional levels and skeletal muscle mass index increased,and their renal function improved.
作者
蔡雪芳
韩宏景
江川
曹文颖
刘翔凌
郑滢
CAI Xuefang;HAN Hongjing;JIANG Chuan;CAO Wenying;LIU Xiangling;ZHENG Ying(The Second People's Hospital of Jingdezhen,Jingdezhen 333000,China)
出处
《护理实践与研究》
2025年第10期1522-1527,共6页
Nursing Practice and Research
基金
景德镇市科学技术局科技计划项目(编号:20231SFZC088)。
关键词
肠内营养支持
维持性血液透析
营养状况
骨骼肌质量
肾功能
Enteral nutrition support
Maintenance hemodialysis
Nutrition status
Skeletal muscle mass
Renal function