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乳腺癌术后患者上肢淋巴水肿发生现状及危险因素研究

Analysis of status quo and risk factors of upper limb lymphedema after breast cancer surgery
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摘要 目的了解乳腺癌术后患者上肢淋巴水肿发生现状及危险因素,为临床制定干预措施提供参考依据。方法采取病例对照回顾性分析2023年6月—2024年6月就诊宁夏某三级甲等医院136例乳腺癌患者,术后并发上肢淋巴水肿的风险因素。通过二元Logistic回归分析明确乳腺癌术后发生上肢淋巴水肿的危险因素。结果发生上肢淋巴水肿的患者37例,发生率为27.21%。二元logistic回归分析显示,与未发生上肢淋巴水肿组相比,年龄、体质指数≥24 kg/m^(2)、术后感染、淋巴结清扫数量≥10个、经历放疗和术后未运动是患者发生上肢淋巴水肿的独立危险因素(P<0.05)。结论年龄较大、肥胖、淋巴结清扫数量多、术后感染、术后放疗、术后未运动是发生上肢淋巴水肿的独立因素,具有较高的预测价值及区分度,可为早期预防淋巴水肿的发生提供临床借鉴。 Objective To investigate the status quo and risk factors of upper limb lymphede⁃ma in breast cancer patients after surgery,and to provide reference for clinical intervention mea⁃sures.Methods A case-control retrospective analysis was taken to analyze the risk factors for postoperative lymphedema of the upper extremity in 136 breast cancer patients who attended a ter⁃tiary-level hospital in Ningxia from June 2023 to June 2024.The risk factors for the occurrence of lymphedema of the upper extremity after breast cancer surgery were clarified by binary logistic re⁃gression analysis.Results In this study,37 patients developed lymphedema of the upper extremi⁃ty,with an incidence of 27.21%.Binary logistic regression analysis showed that compared with the group without upper limb lymphedema,age,body mass index≥24kg/m^(2),postoperative infec⁃tion,number of lymph nodes dissected≥10,radiotherapy and no exercise were independent risk factors for upper limb lymphedema(all P<0.05).Conclusion Older age,obesity,large number of lymph node dissection,postoperative infection,postoperative radiotherapy and no exercise are independent factors for the occurrence of upper limb lymphedema.Findings of this study can pro⁃vide clinical reference for the early prevention of lymphedema after breast cancer surgery.
作者 王彩霞 王艳芸 邹艳杰 牛慧颖 郭侠 WANG Caixia;WANG Yanyun;ZOU Yanjie;NIU Huiying;GUO Xia(Third Department of Medical Oncology,General Hospital of Ningxia Medical University,Yinchuan,Ningxia,750004)
出处 《中西医结合护理》 2025年第9期13-19,共7页 Chinese Journal of Integrative Nursing
基金 宁夏医科大学科研基金资助项目(XM2022049)。
关键词 乳腺癌 上肢淋巴水肿 危险因素 回顾性研究 二元Logistic回归分析 breast cancer lymphedema of the upper extremity risk factors retrospective study binary logistic regression analysis
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