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骨质疏松椎体压缩性骨折椎体强化术后残余疼痛影响因素的Meta分析

Meta-analysis of risk factors for residual pain after vertebral augmentation for osteoporotic vertebral compression fractures
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摘要 目的通过系统评价的方法分析骨质疏松椎体压缩性骨折患者经椎体强化术后残余疼痛的危险因素。方法检索PubMed、Embase、Web of Science、中国知网、万方数据知识服务平台、维普网、中国生物医学文献数据库,筛选骨质疏松椎体压缩性骨折患者椎体强化术后残余疼痛影响因素的相关研究,检索时间为各数据库建库至2024年10月31日。采用RevMan 5.2软件进行Meta分析。结果共纳入18篇文献。Meta分析结果显示,骨质疏松椎体压缩性骨折患者椎体强化术后残余疼痛的影响因素为胸腰筋膜损伤[OR=3.40,95%CI(2.67,4.33)],椎体裂隙征[OR=2.94,95%CI(2.09,4.12)],低骨密度[OR=1.82,95%CI(1.27,2.60)],体质量指数降低[OR=1.08,95%CI(1.03,1.14)],骨水泥分布不满意[OR=2.17,95%CI(1.75,2.71)],术后并发症[OR=4.27,95%CI(2.86,6.38)],椎旁肌退变[OR=6.49,95%CI(4.03,10.47)],术后椎体高度恢复率[OR=1.09,95%CI(1.04,1.15)],多个椎体骨折[OR=3.13,95%CI(2.07,4.73)]。结论骨质疏松椎体压缩性骨折患者在椎体强化术后发生残余疼痛受较多因素影响,医护人员应针对这些因素采取针对性的预防和治疗措施,以降低术后残余疼痛的发生率。 Objective To analyze the risk factors of residual pain after vertebral augmentation in patients with osteoporotic vertebral compression fracture by systematic review.Methods The articles in PubMed,Embase,Web of Science,CNKI,Wanfang Database,VIP Web,and Chinese Biomedical Literature Database were searched to identify the risk factors of residual vertebral pain after reinforcement in patients with osteoporotic vertebral compression fracture,with the time setting from inception till October 31,2024.Meta-analysis was performed using RevMan 5.2 software.Results Eighteen articles were included.The results of meta-analysis showed that the risk factors were thoracolumbar fascial injury[OR=3.40,95%CI(2.67,4.33)],intravertebral vacuum cleft[OR=2.94,95%CI(2.09,4.12)],low bone mineral density[OR=1.82,95%CI(1.27,2.60)],decreased body mass index[OR=1.08,95%CI(1.03,1.14)],unsatisfactory bone cement distribution[OR=2.17,95%CI(1.75,2.71)],postoperative complications[OR=4.27,95%CI(2.86,6.38)],paravertebral muscle degeneration[OR=6.49,95%CI(4.03,10.47)],postoperative vertebral height recovery rate[OR=1.09,95%CI(1.04,1.15)]and multiple vertebral fractures[OR=3.13,95%CI(2.07,4.73)].Conclusion Residual pain in patients with osteoporotic vertebral compression fracture after vertebral reinforcement is affected by many risk factors,and medical staff should take targeted preventive and therapeutic measures to reduce its incidence.
作者 金念 王岚 田航 周金苹 JIN Nian;WANG Lan;TIAN Hang;ZHOU Jinping(School of Nursing,Guizhou University of Traditional Chinese Medicine,Guiyang 550025,China;The Office of Medical Ethics and Discipline,The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550003,China;Department of Orthopedics,Guizhou Provincial Hospital of Orthopedics,Guiyang 550007,China)
出处 《中国临床护理》 2025年第9期581-587,594,共8页 Chinese Clinical Nursing
关键词 残余疼痛 骨质疏松椎体压缩性骨折 椎体强化术 危险因素 META分析 Residual pain Osteoporotic vertebral compression fracture Vertebral augmentation Risk factors Meta analysis
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