摘要
血液制品作为临床救治不可或缺的医疗资源,其安全性直接关系到患者诊疗质量,因此血液安全已成为医疗质量管理的核心环节之一。我国现行的血液安全检测体系仅针对乙型肝炎病毒、丙型肝炎病毒、人类免疫缺陷病毒和梅毒螺旋体4种病原体,这一标准已难以适应当前传染病防控的新形势。随着全球范围内新发再发病原体的不断出现,亟须建立更加完善的病原体筛查体系。文章综述了4种非常规筛查病原体(单纯疱疹病毒、巨细胞病毒、疟原虫和戊肝病毒)对血液安全的影响,详细分析了每种病原体的生物学特性、流行病学特征、传播途径及其对血液安全的潜在威胁,同时探讨了当前筛查方法的局限性,并且提出了相应的改进策略。
As an indispensable medical resource for clinical treatment,the safety of blood products is directly related to the quality of patient diagnosis and treatment.Therefore,blood safety has become one of the core links of medical quality management.China's current blood safety testing system only targets four pathogens:hepatitis B virus,hepatitis C virus,human immunodeficiency virus and Treponemapallidum,which is difficult to adapt to the current new situation of infectious disease prevention and control.With the continuous emergence of new re-pathogens around the world,it is urgent to establish a more complete pathogen screening system.This article reviews the impact on blood safety of four unconventional screening pathogens(herpes simplex virus,Cytomegalovirus,Plasmodium,and hepatitis E virus),and analyzes in detail the biological characteristics,epidemiological characteristics,transmission routes and potential threats to blood safety of each pathogen,discusses the limitations of current screening methods,and proposes improvement strategies.
作者
吴晓彤
孟祥霞
WU Xiaotong;MENG Xiangxia(Department of Blood Supply,Qingdao Blood Center,Qingdao Shandong 266000,China)
出处
《中国卫生标准管理》
2025年第14期160-163,共4页
China Health Standard Management
关键词
新发再发病原体
血液安全
血液筛查
输血传播
血液供应
无偿献血者
emerging and re-emerging pathogen
blood safety
blood screening
transfusion transmission
blood supply
voluntary blood donor
