摘要
目的调查老年肺癌患者服用抗肿瘤药物的依从性现状,分析其影响因素。方法采用便利抽样法选取老年肺癌患者260例为研究对象,对患者的一般资料、用药认知和服用抗肿瘤药物依从性进行问卷调查。采用单因素及多因素Logistic回归分析法分析老年肺癌患者服用抗肿瘤药物依从性的影响因素。结果260例患者的Morisky用药依从性量表得分为(5.78±1.02)分,服药依从性良好183例(70.38%)。单因素分析结果显示,老年肺癌患者服药依从性在文化程度、居住情况、家庭人均月收入、医疗支付方式、用药认知水平、基础服用药物数量差异方面具有统计学意义(P均<0.05);多因素Logistic回归分析结果显示,文化程度、居住情况、医疗支付方式、用药认知水平、基础服用药物数量是老年肺癌患者服药依从性的主要影响因素(P均<0.05)。结论老年肺癌患者服用抗肿瘤药物的依从性还需进一步提高。高中及以上文化、有陪伴、用药认知水平≥6分的老年肺癌患者服药依从性较高,医保或公费支付、基础疾病用药数量≥3种的老年肺癌患者服药依从性较低。
Objective To investigate the current status of compliance with anti-tumor drugs in the elderly patients with lung cancer and to analyze its influencing factors.Methods Convenience sampling was used to select 260 elderly lung cancer patients as the research subjects,and a questionnaire survey was conducted on their general information,medication knowledge,and adherence to anti-tumor drugs.Using univariate and multivariate Logistic regression analyses to analyze the influencing factors of adherence to anti-tumor drugs in elderly lung cancer patients.Results The Morisky Medication Adherence Scale score for 260 patients was(5.78±1.02)points,and 183 patients(70.38%)had good medication adherence.The results of univariate analysis showed that there were statistically significant differences in medication adherence among elderly lung cancer patients in terms of educational level,living conditions,monthly household income per capita,medical payment methods,medication awareness level,and the number of basic medications taken(all P<0.05).The results of multiple Logistic regression analysis showed that education level,living conditions,medical payment methods,medication awareness level,and the number of basic medications taken were the main influencing factors of medication adherence in the elderly lung cancer patients(all P<0.05).Conclusions The compliance of elderly lung cancer patients taking anti-tumor drugs needs to be further improved.Elderly lung cancer patients with high school education or above,companionship,and a medication awareness level of≥6 have higher medication adherence,while elderly lung cancer patients with medical insurance or public payment,and with≥3 types of medication for underlying diseases have lower medication adherence.
作者
季屹红
缪华媛
顾翩翩
郭小红
张晓东
张锦林
JI Yihong;MIAO Huayuan;GU Pianpian;GUO Xiaohong;ZHANG Xiaodong;ZHANG Jinlin(Department of Pharmacy,Cancer Hospital Affiliated to Nantong University,Nantong 226001,China)
出处
《山东医药》
2025年第9期25-28,共4页
Shandong Medical Journal
基金
江苏省药学会-正大天晴医院药学科研基金项目(Q202236)。
关键词
服药依从性
抗肿瘤药物
肺癌
老年人
medication adherence
anti-tumor drugs
lung carcinoma
the aged
