摘要
目的探讨临床病理特征结合术前增强CT影像学特征预测胰头癌患者行根治性手术后极早期复发的价值。方法回顾性分析2010年1月至2022年12月于北京大学第三医院行根治性胰十二指肠切除术的241例胰头癌患者的临床病理与术前增强CT中的影像学特征。结果以术后3个月复发作为极早期复发的阈值,在241例患者中49例患者出现极早期复发,多因素分析显示术前BMI<18.5 kg/m 2(P=0.040)、肿瘤环形强化(P=0.028)、脉管癌栓(P<0.001)以及肿瘤低分化(P=0.013)是极早期复发的独立危险因素。结论临床病理特征结合增强CT影像学特征有助于预测胰头癌术后极早期复发。
Objective To predict very early recurrence after radical resection in patients with pancreatic head cancer by combining preoperative enhanced CT imaging findings and clinicopathological features.Methods The clinicopathological and preoperative enhanced CT imaging features of 241 patients who underwent radical pancreaticoduodenectomy at Peking University Third Hospital from Jan 2010 to Dec 2022 were retrospectively collected and analyzed.Results Using recurrence within 3 months after surgery as the definition for very early recurrence,49 out of 241 patients experienced very early recurrence.Multivariate analysis showed that preoperative BMI<18.5 kg/m²(P=0.040),rim enhancement(P=0.028),lymphovascular invasion(P<0.001),and poor tumor differentiation(P=0.013)were independent risk factors for very early recurrence.ConclusionEnhanced CT imaging features combined with clinicopathological characteristics can predict very early recurrence after resection of pancreatic head cancer.
作者
李源
齐伟峻
邴运韬
王行雁
李磊
马朝来
原春辉
修典荣
Li Yuan;Qi Weijun;Bing Yuntao;Wang Hangyan;Li Lei;Ma Chaolai;Yuan Chunhui;Xiu Dianrong(Department of General Surgery,Peking University Third Hospital,Beijing 100191,China)
出处
《中华普通外科杂志》
北大核心
2025年第9期700-705,共6页
Chinese Journal of General Surgery
关键词
胰腺肿瘤
复发
危险因素
Pancreatic neoplasms
Recurrence
Risk factors
