摘要
人去甲肾上腺素转运蛋白(hNET)在神经嵴源性肿瘤, 如神经母细胞瘤、嗜铬细胞瘤和副神经节瘤中表达。^(18)F-间氟苄胍(MFBG)对hNET具有高度亲和力和特异性, 逐渐被应用于神经嵴源性肿瘤PET/CT显像。该文围绕^(18)F-MFBG PET/CT显像在神经嵴源性肿瘤诊治中的应用进行综述。
The human norepinephrine transporter(hNET)is expressed in neural crest-derived tumors,such as neuroblastoma,pheochromocytoma,and paraganglioma.^(18)F-meta-fluorobenzylguanidine(MFBG)has high affinity and specificity for hNET,and has been gradually applied to PET/CT imaging in neural crest-derived tumors.The application of ^(18)F-MFBG PET/CT imaging in the diagnosis and treatment of neural crest-derived tumors is reviewed in this article.
作者
林学智
刘海波
张国建
Lin Xuezhi;Liu Haibo;Zhang Guojian(The First Clinical Medical College of Inner Mongolia Medical University,Hohot O10050,China;Department of Neurosurgery,the Affiliated Hospital of Inner Mongolia Medical University,Hohhot O10050,China;Department of Nuclear Medicine,the Affiliated Hospital of Inner Mongolia Medical University,Key Laboratory of Nuclear Medicine and Molecular Imaging of Inner Mongolia Autonomous Region,Hohhot 010050,China)
出处
《中华核医学与分子影像杂志》
北大核心
2025年第9期571-576,共6页
Chinese Journal of Nuclear Medicine and Molecular Imaging
基金
内蒙古自治区首府地区公立医院高水平临床专科建设科技项目(2024SGGZ074)
内蒙古医科大学附属医院高层次人才项目("引航"人才)。
