摘要
目的:分析早期宫颈癌及癌前病变筛查中应用人乳头状瘤病毒(HPV)、液基薄层细胞学检测(TCT)联合阴道镜检测对诊断准确度的影响。方法:选取2021年1月~2023年7月本院收治的疑似宫颈癌患者500例,全部患者均接受HPV、TCT以及阴道镜检测,并将病理检测结果作为诊断金标准,对HPV、TCT、阴道镜单独检测以及联合检测的诊断符合率进行比较。结果:联合检测、阴道镜单独检测的宫颈良性病变诊断符合率高于HPV单独检测、TCT单独检测(P<0.05)。联合检测的准确度、特异度、灵敏度阴性预测值、阳性预测值均高于HPV单独检测、TCT单独检测(P<0.05);而联合检测的准确度、灵敏度、阴性预测值高于阴道镜单独检测(P<0.05)。结论:在早期宫颈癌及癌前病变的筛查工作中,应用HPV、TCT联合阴道镜检测具有较好的诊断效能,能提高诊断准确度。
Objective:To analyze the effects of human papillomavirus(HPV)and liquid based thin layer cytology(TCT)combined with colposcopy on diagnostic accuracy in screening for early cervical cancer and precancerous lesions.Methods:A total of 500 patients with suspected cervical cancer were selected,all of whom were admitted from January 2021 to July 2023.All patients received HPV,TCT and colposcopy tests,and pathological test results were taken as the diagnostic gold standard.The diagnostic coincidence rate and diagnostic value of HPV,TCT and colposcopy tests alone and combined tests were compared.Results:The diagnosis coincidence rate of cervical benign lesions by combined detection and colposcopy alone was significantly higher than that by HPV alone and TCT alone(P<0.05).The accuracy,specificity,sensitivity negative predictive value and positive predictive value of combined detection were significantly higher than those of HPV and TCT alone detection(P<0.05).The accuracy,sensitivity and negative predictive value of combined detection were significantly higher than those of colposcopy alone(P<0.05).Conclusion:In the screening of early cervical cancer and precancerous lesions,the application of HPV and TCT combined colposcopy has better diagnostic efficacy and can improve the diagnostic accuracy.
作者
王晶晶
WANG Jing-jing(Department of Obstetrics and Gynecology,Suizhou Maternal and Child Health Care Hospital,Hubei Suizhou 441300)
出处
《中国医疗器械信息》
2025年第18期132-134,共3页
China Medical Device Information
关键词
人乳头状瘤病毒
癌前病变
液基薄层细胞学检测
早期宫颈癌
阴道镜
human papilloma virus
precancerous lesions
liquid based thin layer cytological detection
early cervical cancer
colposcope
