摘要
当前放射治疗已经成为临床上治疗宫颈癌Ⅱb期及以上患者的首选方案,但是在放射治疗时,药物在杀灭肿瘤细胞的同时,也会对身体的正常细胞造成一定的影响,产生各种毒副反应,其中急性反射性皮炎便是其中常见的毒副反应,其在行放射治疗的宫颈癌患者中发生率高达93.8%,主要累及患者的会阴部,包含肛门四周、外阴、腹股沟、尾骶部等,导致患者放疗的依从性下降,影响了患者预后。当前临床上关于宫颈癌急性反射性皮炎的防治以药物与护理措施为主,虽然能够在一定程度降低急性放射性皮炎的发生率,但是效果不尽如人意。因此还需要积极探寻更高效、更简单的方法防治宫颈癌急性放射性皮炎。
At present,radiotherapy has become the preferred treatment for patients with cervical cancer stageⅡb and above.However,during radiotherapy,drugs not only kill tumor cells,but also affect normal cells of the body,resulting in various toxic and side effects,among which acute reflex dermatitis is a common toxic and side effect.The incidence of cervical cancer in patients undergoing radiotherapy is as high as 93.8%,mainly involving the perineum of patients,including perianus,vulva,groin,caudal sacral region,etc.,leading to a decline in patients’compliance with chemotherapy and affecting the prognosis of patients.The current clinical prevention and treatment of acute reflex dermatitis of cervical cancer is mainly based on drugs and nursing measures,although it can reduce the incidence of acute radiation dermatitis to a certain extent,but the effect is not satisfactory.Therefore,it is also necessary to actively explore more efficient and simpler methods to prevent and treat acute radiation dermatitis of cervical cancer.
作者
王阳
吕宏英
WANG Yang;LV Hong-ying(Zhejiang University School of Medicine Affiliated Obstetrics and Gynecology Hospital,Zhejiang Hangzhou 310006)
出处
《中国医疗器械信息》
2025年第17期59-62,共4页
China Medical Device Information
基金
浙江省医药卫生科技计划项目(项目名称:皮肤氧疗装置在宫颈癌急性放射性皮炎防治中的开发和应用研究,项目编号:2024KY1149)
国家实用新型专利(专利号:ZL202221632974.8)。
关键词
宫颈癌
急性放射性皮炎
皮肤氧疗装置
cervical cancer
acute radiation dermatitis
skin oxygen therapy device