摘要
心血管疾病与癌症是对人类健康威胁最大的两种疾病,二者之间的相关性日益引起人们重视。氨基末端脑钠肽前体(NT-proBNP)是心功能不全的生物标志物,在评估患者心脏功能及心血管疾病预后方面起着重要作用。此外,NT-proBNP在监测肿瘤治疗相关的心脏毒性、评估肿瘤患者预后及肿瘤诊断方面具有一定价值,而肿瘤又可影响NT-proBNP的合成。本文对NT-proBNP与肿瘤的相关性进行综述,以提升对NT-proBNP在肿瘤领域潜在应用价值的认识。
Cardiovascular diseases and cancer represent the two greatest threats to human health,and the correlation between them has garnered increasing attention.N-terminal pro-brain natriuretic peptide(NT-proBNP),as a biomarker of cardiac dysfunction,plays an important role in assessing patients′cardiac function and the prognosis of cardiovascular diseases.Additionally,NT-proBNP has shown potential value in monitoring cardiotoxicity caused by tumor treatment,evaluating the prognosis of cancer patients,aiding tumor diagnosis.Moreover,tumors affect the synthesis of NT-proBNP.In this article,we reviewed the correlation between NT-proBNP and tumors,aiming to enhance the understanding of potential application of NT-proBNP in oncology.
作者
王溢豪
胡舜英
Wang Yihao;Hu Shunying(Department of Cardiology,Sixth Medical Center,Chinese PLA General Hospital,Beijing 100853,China)
出处
《中华老年多器官疾病杂志》
2025年第9期717-720,共4页
Chinese Journal of Multiple Organ Diseases in the Elderly
基金
国家自然科学基金(82173450)。
关键词
氨基末端脑钠肽前体
恶性肿瘤
心脏毒性
癌症预后
癌症诊断
N-terminal pro-brain natriuretic peptide
cancer
cardiotoxicity
cancer prognosis
cancer diagnosis
