摘要
目的:探索舌象信息化特征在延年九转法干预气虚证慢性疲劳综合征(CFS)患者中的应用。方法:2022年7月1日至2023年6月30日在上海中医药大学进行一项为期8周的随机临床对照试验。将招募的124例气虚证CFS患者随机分为延年九转法组(PLWNT组)和认知行为组(CBT组)。主要结果是从基线到第8周的多维疲劳量表(MFI-20)的变化。次要结果采用TFDA-1型数字舌面诊仪采集两组患者舌象图像RGB、HSI、Lab、YCrCb颜色空间指标。结果:治疗8周后,PLWNT组在一般疲劳、身体疲劳、活动减少、兴趣减少和精神疲劳试验前后的平均差异分别为4.290[95%CI(3.433,5.147)]、4.339[95%CI(3.511,5.166)]、4.355[95%CI(3.464,5.24)]、3.016[95%CI(2.120,3.91)]和4.355[95%CI(3.410,5.300)](P<0.001);PLWNT与CBT组比较,在一般疲劳、身体疲劳、活动减少的MFI-20差异分别为-2.110(-3.423~-0.797)、-2.699(-4.113~-1.284)、-1.795(-3.144~-0.445)(P<0.05,P<0.01)。舌象图像指标TB-I、TB-L、TB-Cr、TB-Cb、TB-CON、TB-MEAN、TB-Y、TC-I、TC-L、TC-a、TC-Y显著高于干预前(P<0.05),TB-S、perA1I、ASM显著低于干预前(P<0.05)PLWNT组与CBT组比较,舌象图像指标TB-b、TB-Cb、TC-Cr、perAIl差异具有统计学意义(P<0.05)。结论:PLWNT干预8周后,舌象图像指标趋向于淡红舌、薄白苔的改善方向。
Objective:To explore the pattern of tongue image characteristics of chronic fatigue syndrome(CFS)patients after Prolong Life With Nine Turn Method qigong intervention.Methods:Using TFDA-1 digital tongue facial diagnostic instrument,tongue image data of 124 chronic fatigue syndrome qi deficiency people were included and randomly divided into Prolong Life With Nine Turn Method(PLWNT)and cognitive behavioural group(CBT).Using RGB,HSI,Lab,and YCrCb colour space metrics,we analysed the tongue image characteristics of the CFS population after 8 weeks of intervention with PLWNT and CBT.Results:After 8 weeks of intervention with the PLWNT,the tongue image indexes TB-R,TB-G,TB-B,TB-I.TB-L,TB-Cr,TB-Cb,TB-CON,TB-MEAN,TB-Y,TC-R,TC-G,TC-B,TC-I,TC-L,TC-a,TC-Y were significantly higher than those before the intervention(P<0.01);the tongue image indexes TB-S,TB-i,TC-a,TC-y were significantly higher than those before the intervention(P<0.O1);and the tongue image indexes TB-S,TB-i,TB-i,TC-a,TC-y were significantly higher than those before the intervention(P<0.01).image indexes TB-S,perAll,and ASM were lower than before intervention(P<0.01).Compared with the CBT group,the differences in tongue image indexes of TB-b,TB-Cb,TC-Cr,and perAll in the PLWNT group were statistically significant(P<0.05).Conclusion:The colour saturation and brightness of tongue images of CFS patients increased after PLWNT intervention,tending to white and red;the tongue texture tended to be more delicate,and the tongue coating became thinner.
作者
谢芳芳
顾元嘉
谢超群
马健文
岳虹妤
胡晓娟
姚斐
许家佗
XIE Fangfang;GU Yuanjia;XIE Chaoqun;MA Jianwen;YUE Hongyu;HU Xiaojuan;YAO Fei;XU Jiatuo(Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Shanghai Municipal Hospital of Traditional Chinese Medicine,Shanghai 200071,China)
出处
《中华中医药杂志》
北大核心
2025年第7期3868-3875,共8页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
中国博士后科学基金第18批特别资助(No.2025T181083)
国家资助博士后研究人员计划(No.GZC20252639)
国家自然科学基金面上项目(No.82374610)
国家自然科学基金青年项目(No.82105038)
国家重点研发计划中医药现代化研究重点专项(No.2017YFC1703301)
关键词
延年九转法
气功
慢性疲劳综合征
舌象
中医诊断
Prolong Life With Nine Turn Method
Qigong
Chronic fatigue syndrome(CFS)
Tongue image
TCM diagnosis
