摘要
头颈部肿瘤(HNC)具有解剖结构复杂、病理类型多样、治疗方式多元化等特点,传统临床分期难以满足精准诊疗需求,亟需多维度的信息整合以优化诊疗策略。影像组学(Radiomics)可以整合不同成像模式(如结构、功能及分子影像)提供更多内在生物学信息,进一步转化为高维定量特征并链接到预后、疗效及毒性反应等临床结局,助力HNC的精确诊断、分期、个体化决策和毒性反应管理。本文梳理了影像组学在头颈部肿瘤中的最新研究进展,旨在探讨其临床价值、技术挑战及未来发展方向。
Head and neck cancer(HNC)is characterized by complex anatomy,diverse pathological types,and heterogeneous treatment modalities.Conventional clinical staging falls short in meeting the demands of precision medicine,creating an urgent need for multi-dimensional information integration to optimize diagnostic and therapeutic strategies.Radiomics,by integrating various imaging modalities(such as structural,functional,and molecular imaging),can extract intrinsic biological information and convert it into high-dimensional quantitative features.These features can be linked to clinical outcomes such as prognosis,treatment response,and toxicity,thereby facilitating precise diagnosis,accurate staging,individualized decision-making,and toxicity management in HNC.This article reviews recent advances in radiomics research for head and neck tumors,discusses its clinical value,technical challenges,and future directions.
作者
冯梅
尹清萍
李璐
范铭
FENG Mei;YIN Qingping;LI Lu;FAN Ming(The Third People's Hospital of Sichuan Province,Chengdu 610100,China;Sichuan Cancer Hospital,Sichuan Key Laboratory of Precision Radiotherapy,Sichuan Provincial Clinical Research Center for Cancer,Sichuan Cancer Prevention and Treatment Center,Department of Radiotherapy,Affiliated Cancer Hospital of University of Electronic Science and Technology of China,Chengdu 610041,China)
出处
《西部医学》
2025年第9期1254-1257,共4页
Medical Journal of West China
基金
四川省卫生健康委员会医学科技项目(24LCYJPT09)
成都市科学技术局技术创新研发项目(2024-YF05-02377-SN)。
关键词
头颈部肿瘤
影像组学
精准治疗
毒性管理
Head and neck neoplasms
Radiomics
Precision medicine
Toxicity management
