摘要
目的比较不同剂量羟考酮与舒芬太尼在腹腔镜全子宫切除术中的应用价值。方法选取2023年1月至12月江西省人民医院收治的90例择期行腹腔镜下全子宫切除术患者作为研究对象,按照抽签法分为A组、B组和S组,每组各30例。A组术中采用羟考酮维持量0.05 mg/(kg·h),B组术中采用间断推注羟考酮0.1 mg/kg,S组术中采用间断推注舒芬太尼0.1μg/kg。记录并比较三组患者的术后疼痛评分、拔管时间、恢复室停留时间、首次下床时间、首次排气时间、住院时间,以及术后头晕、术后恶心呕吐的发生情况。结果A组和B组的首次下床时间、首次排气时间和住院时间均短于S组,差异有统计学意义(P<0.05)。B组的拔管时间及恢复室停留时间均长于A组、S组,差异有统计学意义(P<0.05);A组的拔管时间及恢复室停留时间均长于S组,差异有统计学意义(P<0.05)。三组的术后疼痛评分与术后头晕、术后恶心呕吐发生率比较,差异无统计学意义(P>0.05)。结论羟考酮和舒芬太尼在腹腔镜全子宫切除手术中均可安全使用。相较于舒芬太尼,全程应用羟考酮可促进腹腔镜全子宫切除术患者术后胃肠功能恢复。
Objective To compare the application value of different doses of Oxycodone and Sufentanil in laparoscopic total hysterectomy.Methods A total of 90 patients undergoing laparoscopic total hysterectomy in Jiangxi Provincial People's Hospital from January to December 2023 were selected as the research objects.According to the lottery method,they were divided into group A,group B and group S,with 30 cases in each group.Group A was treated with 0.05 mg/(kg·h)Oxycodone as maintenance dose during operation.In group B,Oxycodone 0.1 mg/kg was injected intermittently during operation.In group S,Sufentanil 0.1μg/kg was injected intermittently during operation.The postoperative pain score,extubation time,recovery room stay time,first ambulation time,first exhaust time,hospitalization time,and the incidences of postoperative dizziness,postoperative nausea and vomiting were recorded and compared among the three groups.Results The first ambulation time,first exhaust time and hospitalization time in group A and group B were shorter than those in group S,and the differences were statistically significant(P<0.05).The extubation time and recovery room stay time in group B were longer than those in group A and group S,and the differences were statistically significant(P<0.05).The extubation time and recovery room stay time in group A were longer than those in group S,and the differences were statistically significant(P<0.05).There were no significant differences in the postoperative pain score and the incidences of postoperative dizziness,postoperative nausea and vomiting among the three groups(P>0.05).Conclusion Both Oxycodone and Sufentanil can be safely used in laparoscopic total hysterectomy.Compared with Sufentanil,Oxycodone can promote the recovery of gastrointestinal function in patients undergoing laparoscopic total hysterectomy.
作者
刘仲玉
苏华凤
郭善亮
张明生
杨品娥
LIU Zhongyu;SU Huafeng;GUO Shanliang;ZHANG Mingsheng;YANG Pin′e(Department of Anesthesiology and Pain,Jiangxi Provincial People's Hospital,the First Affiliated Hospital of Nanchang Medical College,Jiangxi Province,Nanchang330000,China;Department of Anesthesiology,Yujiang District People's Hospital of Yingtan,Jiangxi Province,Yingtan335200,China;Department of Quality Control,Jiangxi Provincial People's Hospital,the First Affiliated Hospital of Nanchang Medical College,Jiangxi Province,Nanchang330000,China)
出处
《中国当代医药》
2025年第23期96-99,105,共5页
China Modern Medicine
基金
白求恩公益基金会恩泽疼痛管理医学研究项目(ezmr2022-075)。
关键词
羟考酮
腹腔镜全子宫切除术
舒芬太尼
麻醉
Oxycodone
Laparoscopic total hysterectomy
Sufentanil
Anaesthesia
