摘要
复发性自然流产(RSA)严重影响育龄夫妇的生育健康,其发病机制复杂,至今仍有部分病因不明。蜕膜巨噬细胞作为母胎界面重要的免疫细胞,在维持正常妊娠过程中发挥着关键作用。文章综合近年来的研究成果,对蜕膜巨噬细胞的表型、功能,以及其与RSA的关系进行综述,旨在为深入理解RSA的发病机制及探索新的治疗策略提供参考。
Recurrent spontaneous abortion(RSA)seriously affects the reproductive health of childbearing couples.Its pathogenesis is complex,and some causes remain unclear to date.As important immune cells at the maternal-fetal interface,decidual macrophages play a crucial role in maintaining normal pregnancy.This article synthesizes the research findings in recent years and reviews the phenotypes,functions of decidual macrophages,and their relationship with RSA,aiming to provide a reference for a deeper understanding of the pathogenesis of RSA and the exploration of new treatment strategies.
作者
张晓艳(综述)
赵欣(综述)
王丽静(综述)
瓮占平(审校)
Zhang Xiaoyan;Zhao Xin;Wang Lijing;Weng Zhanping(School of Clinical Medicine,Shandong Second Medical University,Shandong,Weifang 261053,China;不详)
出处
《疑难病杂志》
2025年第9期1147-1152,共6页
Chinese Journal of Difficult and Complicated Cases
基金
山东省自然科学基金项目(ZR2023QH077)。
关键词
复发性自然流产
蜕膜巨噬细胞
研究进展
Recurrent spontaneous abortion
Decidual macrophages
Research progress
