摘要
自身免疫性皮肤病是一类由于自身免疫系统紊乱,导致免疫系统对自身皮肤组织产生损害而引起的皮肤病。限时进食作为一种新型的饮食模式,是一种减肥和改善代谢的饮食方法,然而其在自身免疫性皮肤病中的潜在益处尚未得到广泛研究。现有研究认为,限时进食能够通过调节昼夜节律和炎症细胞因子的表达水平,缓解自身免疫性皮肤病皮损的形成。与传统的禁食模式相比,限时进食具有更好的安全性、依从性和执行性,可在我国自身免疫性皮肤病患者中进行推广,并为自身免疫性皮肤病的非药物性治疗提供思路。
Autoimmune skin diseases refer to a group of dermatological disorders where immune system dysregulation leads to damage of self-skin tissues.Time-restricted eating(TRE),a novel dietary pattern proven effective for weight loss and metabolic health improvement,has seen limited exploration of its potential benefits in autoimmune skin diseases.Current evidence suggests that TRE alleviates lesion formation in autoimmune skin diseases by regulating circadian rhythms and inflammatory cytokine expression.Compared with traditional fasting models,TRE offers superior safety,compliance,and feasibility,making it a promising non-pharmacological approach for Chinese patients with autoimmune skin diseases.This review highlights TRE's potential as a scalable therapeutic strategy and provides insights for developing non-drug interventions in autoimmune dermatology.
作者
李嘉毓
于宁
张怡
LI Jiayu;YU Ning;ZHANG Yi(Department of of Dermatology,Shanghai Skin Disease Hospital,Shanghai 200443,China)
出处
《实用皮肤病学杂志》
2025年第4期288-292,共5页
Journal of Practical Dermatology
基金
国家自然科学基金面上项目(82273515)。
关键词
自身免疫性皮肤病
限时进食
间歇性禁食
炎症标志物
昼夜节律
Autoimmune skin diseases
Time-restricted eating
Intermittent fasting
Inflammatory markers
Circadian rhythm
