摘要
目的:分析老年冠心病合并2型糖尿病患者住院期间发生心房颤动的影响因素。方法:选取2022年10月至2024年3月该院收治的120例老年冠心病合并2型糖尿病患者进行横断面研究,统计老年冠心病合并2型糖尿病患者住院期间心房颤动发生情况,采用Logistic回归分析老年冠心病合并2型糖尿病患者住院期间发生心房颤动的影响因素。结果:120例冠心病合并2型糖尿病患者住院期间发生心房颤动51例,发生率为42.50%(51/120),设为发生组,其余设为未发生组;发生组年龄>75岁、合并高血压、未服用血管紧张素转化酶抑制剂(ACEI)/血管紧张素受体阻滞剂(ARB)、N末端B型利钠肽原(NT-proBNP)>325 ng/L、左心室舒张末期内径(LVEDD)>4.5 cm、超敏肌钙蛋白T(hs-cTnT)>0.014μg/L、总胆红素(TBIL)<10.2μmol/L、总胆固醇(TC)≥5.18 mmol/L等占比均高于未发生组,差异有统计学意义(P<0.05);经Logistic回归分析结果显示,年龄>75岁、合并高血压、未服用ACEI/ARB、NT-proBNP>325 ng/L、LVEDD>4.5 cm、hs-cTnT>0.014μg/L、TBIL<10.2μmol/L、TC≥5.18 mmol/L等均为影响老年冠心病合并2型糖尿病患者住院期间发生心房颤动的危险因素(OR>1,P<0.05)。结论:年龄>75岁、合并高血压、未服用ACEI/ARB、NT-proBNP>325 ng/L、LVEDD>4.5 cm、hs-cTnT>0.014μg/L、TBIL<10.2μmol/L、TC≥5.18 mmol/L等均为影响老年冠心病合并2型糖尿病患者住院期间发生心房颤动的危险因素。
Objective:To analyze influencing factors of atrial fibrillation during hospitalization in elderly patients with coronary heart disease and type 2 diabetes mellitus.Methods:A cross-sectional study was conducted on 120 elderly patients with coronary heart disease and type 2 diabetes admitted to the hospital from October 2022 to March 2024.The incidence of atrial fibrillation in the elderly patients with coronary heart disease and type 2 diabetes mellitus during hospitalization was mellitus.Logistic regression was used to analyze the influencing factors of atrial fibrillation during hospitalization in the elderly patients with coronary heart disease and type 2 diabetes mellitus.Results:51 cases of atrial fibrillation occurred in the 120 patients with coronary heart disease and type 2 diabetes during hospitalization,the incidence rate was 42.50%(51/120),which was set as the occurrence group,and the rest was set as the non-occurrence group.The proportions of the patients with age>75 years old,combined hypertension,no angiotensin converting enzyme inhibitors(ACEI)/angiotensin receptor blockers(ARB),N-terminal B-type natriuretic peptide precursor(NT-proBNP)>325 ng/L,left ventricular end-diastolic diameter(LVEDD)>4.5 cm,high sensitivity cardiac troponin(hs-cTnT)>0.014μg/L,total bilirubin(TBIL)<10.2μmol/L and total cholesterol(TC)≥5.18 mmol/L in the occurrence group were higher than those in the nonoccurrence group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that age>75 years old,combined hypertension,no ACEI/ARB,NT-proBNP>325 ng/L,LVEDD>4.5 cm,hs-cTnT>0.014μg/L,TBIL<10.2μmol/L and TC≥5.18 mmol/L are the risk factors for atrial fibrillation in the elderly patients with coronary heart disease and type 2 diabetes mellitus during hospitalization(OR>1,P<0.05).Conclusions:Age>75 years old,hypertension,no ACEI/ARB,NT-proBNP>325 ng/L,LVEDD>4.5 cm,hs-cTnT>0.014μg/L,TBIL<10.2μmol/L,TC≥5.18 mmol/L were the risk factors for atrial fibrillation in the elderly patients with coronary heart disease and type 2 diabetes mellitus during hospitalization.
作者
杨雪珂
魏伟丽
YANG Xueke;WEI Weili(3^(rd)Department of Cardiovascular Internal Medicine of the People’s Hospital of Anyang City,Anyang 455000 Henan,China)
出处
《中国民康医学》
2025年第17期1-4,共4页
Medical Journal of Chinese People’s Health
关键词
老年
冠心病
2型糖尿病
心房颤动
影响因素
Elderly
Coronary heart disease
Type 2 diabetes mellitus
Atrial fibrillation
Influencing factor