摘要
阿苯达唑是一种苯并咪唑类化合物,凭借双重作用机制发挥抗寄生虫活性,广泛应用于棘球蚴、丝虫和鞭毛虫等多种寄生虫感染的治疗,其中肝棘球蚴病为重要的适应证之一。本文针对近年来国内外关于阿苯达唑在肝棘球蚴病的应用及研究现状做一综述,为阿苯达唑在肝棘球蚴病临床治疗的优化提供新的思路与参考。
Albendazole(ABZ)is a benzimidazole compound that exerts antiparasitic activity by virtue of its dual mechanism of action.It is widely used in the treatment of various parasitic infections such as echinococcosis,filariasis,and flagellates,among which hepatic echinococcosis(also known as"hydatid disease")is one of the important indications.This article reviews the application and research status of ABZ in hepatic echinococcosis at home and abroad in recent years,aiming to provide new ideas and references for the optimization of ABZ in the clinical treatment of hepatic echinococcosis.
作者
罗彩霞
马洁
王志鑫
王展
范明嫄
王海久
LUO Caixia;MA Jie;WANG Zhixin;WANG Zhan;FAN Mingyuan;WANG Haijiu(School of Medicine,Qinghai University,Xining,Qinghai 810016,China;The Second Department of General Surgery,the Affiliated Hospital of Qinghai University,Xining,Qinghai 810001,China)
出处
《热带医学杂志》
2025年第7期995-997,1001,共4页
Journal of Tropical Medicine
基金
青海省科技厅项目(2017-SF-L2)
青海大学附属医院肝胆外科(包虫病)国家临床重点专科建设项目(青卫健办-125号)。
关键词
阿苯达唑
肝棘球蚴病
Albendazole
Hepatic echinococcosis
