摘要
目的 对湖北省2023—20204年报告的猴痘确诊病例的流行病学特征及临床表现进行分析,为优化区域猴痘防控策略和应对新发再发传染病提供参考依据。方法 资料来源于“全国传染病报告信息管理系统”中截至2024年12月31日报告的现住址为湖北省的猴痘确诊病例个案信息,以及猴痘病例的流行病学调查报告,系统分析其流行病学特征,包括人口学分布、临床表现及防控措施效果。结果 湖北省2023—2024年累计确诊63例猴痘病例,以散发为主,集中在2023年7—9月,2024年以来处于低流行水平。病例的主要特征为男男性行为者(men who have sex with men, MSM)人群(87.3%)、青壮年(20~49岁占88.4%)、未婚(68.3%)和家务待业(36.5%),25.4%为艾滋病患者。93.7%为主动就诊发现。首发症状以皮疹(60.3%)和发热(20.6%)为主,主要临床症状为皮疹(96.8%)、发热(63.5%)和皮疹瘙痒(27.0%)、淋巴结肿大(22.2%)。病例发病至就诊时间间隔为0~29 d,M(P_(25),P_(75))为9(6,13)d。病例潜伏期为0~25 d,M(P_(25),P_(75))为7(4,10)d。猴痘纳入“乙类乙管”后,湖北省病例发病至就诊时间间隔缩短。结论 湖北省猴痘防控工作有待加强,应持续加强猴痘监测、利用艾滋病防治综合干预服务体系对MSM人群和大学生等重点人群健康教育以及综合医院医务人员培训。
Objective To analyze epidemiological characteristics and clinical manifestations of confirmed mpox cases reported in Hubei Province from 2023 to 2024,so as to provide scientific basis and reference for optimizing regional mpox control and prevention strategies and dealing with emerging infectious diseases.Methods The data included individual case information and epidemiological investigation report of on the confirmed mpox cases whose current residence is in Hubei Province reported in the National Infectious Disease Reporting Information Management System as of December 31,2024.The epidemiological characteristics,including demographic distribution,clinical manifestations and the effect of prevention and control measures,were systematically analyzed.Results The total of 63 mpox cases confirmed in Hubei Province from 2023 to 2024 were mainly sporadic,which was concentrated from July to September 2023 and was at a low epidemic level since 2024.The main characteristics of the cases were men who have sex with men(87.3%),young adults(88.4%aged 20 to 49 years),unmarried(68.3%)and unemployed(28.8%),and 25.4%were AIDS patients.93.7%were found through proactive medical consultation.The initial symptoms were rash(60.3%)and fever(20.6%),and the main clinical symptoms were rash(96.8%),fever(63.5%),itchy rash(27.0%),and enlarged lymph nodes(22.2%).The interval between the onset of disease to the time of medical consultation was 0-29 days,with M(P_(25),P_(75))of 9(6,13)days.The incubation period of the cases was 0-25 days,with M(P_(25),P_(75))of 7(4,10)days.After mpox was included in the management of Class B infectious diseases in China,the interval between the onset of disease to the time of medical consultation in our province was shortened.Conclusion The control and prevention of mpox in our province needs to be strengthened.We should continuously strengthen the monitoring of mpox,using the comprehensive intervention service system of AIDS prevention and treatment to provide health education for key groups such as MSM and college students,along with strengthen the training of medical staff in general hospitals.
作者
陈楚鼎
吴杨
官旭华
CHEN Chuding;WU Yang;GUAN Xuhua(Hubei Provincial Center for Disease Control and Prevention,Wuhan,Hubei 430079,China)
出处
《中国热带医学》
北大核心
2025年第7期813-818,共6页
China Tropical Medicine
基金
2023—2026年国家疾病预防控制局公共卫生人才培养支持项目(2023-10)
2021—2025年湖北省公共卫生领军人才项目(2021-11)。
