摘要
光疗在白癜风治疗中具有重要地位。窄谱中波紫外线(narrow-band ultraviolet B,NB-UVB)是目前临床治疗非节段型白癜风的一线光疗手段。近年来,可见光逐渐成为治疗白癜风的一种新兴方式。研究表明,氦氖激光对于节段型白癜风具有较好的治疗效果,蓝光对局限型白癜风治疗效果较好,而NB-UVB更适合散发或泛发型白癜风的治疗。不同的光疗方式具有不同的作用特点,诱导白斑复色的作用机制涉及多种生物蛋白以及相关信号通路。本文就近年来几种光疗手段在白癜风治疗中的研究进展进行综述。
Phototherapy plays a significant role in vitiligo treatment.Narrow-band ultraviolet B(NB-UVB)remains the first-line phototherapy for non-segmental vitiligo in clinical practice.In recent years,visible light has emerged as a novel therapeutic approach for vitiligo.Studies indicate that helium-neon laser demonstrates superior efficacy in segmental vitiligo,blue light is more effective for localized vitiligo,and NB-UVB is better suited for generalized or extensive vitiligo.Different phototherapy modalities exhibit distinct mechanisms of action,involving multiple biological proteins and signaling pathways in melanocyte activation and repigmentation.This review sum-marizes recent advances in phototherapy for vitiligo treatment.
作者
高榕荫
万聪翀
殷川伟
吕金鹏
GAO Rongyin;WAN Congchong;YIN Chuanwei;Lü Jinpeng(Department of Pharmacy,the First People′s Hospital of Changzhou,the Third Affiliated Hospital of Soochow University,Changzhou 213000,Jiangsu,China;不详)
出处
《实用医学杂志》
北大核心
2025年第17期2646-2652,共7页
The Journal of Practical Medicine
基金
国家自然科学基金资助项目(编号:82103752)。
