摘要
慢性胰腺炎是一种胰腺的形态与功能均出现进行性、不可逆损伤的疾病。其病程中,炎症与纤维化过程可引发一系列严重的局部并发症,具体包括胰管结石、主胰管狭窄、胰腺假性囊肿、胆道狭窄、十二指肠梗阻、胰源性门静脉高压,严重时甚至可能进展为胰腺癌。与此同时,随着胰腺功能的逐渐丧失,患者还会出现内分泌及外分泌功能不全的情况。鉴于慢性胰腺炎并发症的复杂性与严重性,本文将对慢性胰腺炎并发症的诊疗进展展开综述,以期为临床实践提供有益的参考。
Chronic pancreatitis is a disease characterized by irreversible changes in the morphology and function of the pancreas.During its course,the inflammatory and fibrotic processes can lead to a range of severe local complications,including pancreatic duct stones,main pancreatic duct stenosis,pancreatic pseudocysts,bile duct stenosis,duodenal obstruction,pancreatic portal hypertension,and in severe cases,even pancreatic cancer.Concurrently,as pancreatic function progressively deteriorates,patients may develop endocrine and exocrine insufficiency.Given the complexity and severity of the complications associated with chronic pancreatitis,this article will review the diagnostic and therapeutic advancements in the management of these complications,aiming to provide useful references for clinical practice.
作者
刘文静
李明阳
LIU Wenjing;LI Mingyang(Department of Gastroenterology&Hepatology,the First Medical Center,Chinese PLA General Hospital,Beijing 100853,China)
出处
《胃肠病学和肝病学杂志》
2025年第9期1252-1257,共6页
Chinese Journal of Gastroenterology and Hepatology
关键词
慢性胰腺炎
胰管结石
主胰管狭窄
胰腺假性囊肿
胆道梗阻
胰源性门脉高压
胰腺癌
3c型糖尿病
胰腺外分泌功能不全
Chronic pancreatitis
Pancreatic duct stones
Main pancreatic duct stenosis
Pancreatic pseudocysts
Biliary obstruction
Pancreatic portal hypertension
Pancreatic cancer
Type 3c diabetes mellitus
Pancreatic exocrine insufficiency
