摘要
目的探究CT参数及患者血清hs-CRP、尿酸、血脂与急性肺栓塞(APE)患者预后不良的相关性。方法回顾性分析2021年1月—2023年11月本院收治的APE患者110例的临床资料,根据是否预后不良分为预后不良组和预后良好组,用单因素及logistic回归分析患者预后不良的独立影响因素,用受试者工作特征(ROC)曲线分析这些指标对患者预后不良的预测效能。结果本研究110例患者中,有36例发生预后不良,预后不良发生率为32.72%;单因素分析显示,血清hs-CRP、HDL、LDL、尿酸、PA/AO、RV/LV、SVC均是APE患者预后不良的影响因素(均P<0.05);logistic回归分析显示,PA/AO、RV/LV、SVC、血清hs-CRP、HDL、LDL、尿酸均是APE患者预后不良的独立影响因素(均P<0.05);ROC曲线显示,PA/AO、RV/LV、SVC、血清hs-CRP、HDL、LDL、尿酸及联合预测的曲线下面积(AUC)分别为0.743、0.669、0.852、0.784、0.653、0.696、0.809、0.974,联合预测优于单独预测(P<0.05)。结论CT相关参数及患者血清hs-CRP、尿酸、血脂相关指标均为APE患者预后不良的独立影响因素,且在APE患者预后不良中具良好预测价值。
Objective To investigate the correlation between CT parameters,serum high-sensitivity C-reactive protein(hs-CRP),uric acid,lipids and poor prognosis in patients with acute pulmonary embolism(APE).Methods The clinical data of 110 patients with APE admitted to our hospital from January 2021 to November 2023 were retrospectively analyzed.According to whether they had poor prognosis,they were divided into the poor prognosis group and the good prognosis group.Univariate and logistic regression analyses were used to analyze the independent influencing factors of poor prognosis.The receiver operating characteristic(ROC)curve was used to analyze the predictive efficacy of these indicators for poor prognosis.Results In this study,36 of 110 patients had poor prognosis,with a poor prognosis rate of 32.72%.Univariate analysis showed that serum hs-CRP,HDL,LDL,uric acid,PA/AO,RV/LV,and SVC were all influencing factors for poor prognosis of patients with APE(all P<0.05).Logistic regression analysis showed that serum hs-CRP,HDL,LDL,uric acid,PA/AO,RV/LV,and SVC were all independent influences on the poor prognosis of APE patients(all P<0.05).ROC analysis showed that the area under the curve(AUC)of serum PA/AO,RV/LV,SVC,serum hs-CRP,HDL,LDL,and uric acid,predicted individually and in combination were 0.743,0.669,0.852,0.784,0.653,0.696,0.809,and 0.974,respectively,and the joint prediction was better than the individual prediction(P<0.05).Conclusions CT-related parameters and patients'serum hs-CRP,uric acid,and lipids are independent influencing factors of poor prognosis in patients with APE,and have good predictive value for poor prognosis in patients with APE.
作者
李苗苗
罗志武
Li Miaomiao;Luo Zhiwu(Putian First Hospital,Putian,Fujian 351100,China;Putian Emergency Center,Putian,Fujian 351100,China)
出处
《齐齐哈尔医学院学报》
2025年第16期1547-1551,共5页
Journal of Qiqihar Medical University
