摘要
目的探讨食管癌术后吻合口狭窄的危险因素。方法选取2015年7月至2024年6月在大理大学第一附属医院行食管癌根治术的200例患者作为研究对象,根据患者有无发生吻合口良性狭窄分为狭窄组(n=100)和非狭窄组(n=100)。比较两组患者的首次进食时间、手术时间、非线型器械吻合、吻合口瘘等情况,分析食管癌根治术后良性吻合口狭窄的独立危险因素。结果患者术后首次进食时间晚、非线型器械吻合、吻合口瘘、术后持续性低氧血症是食管癌患者颈部吻合术后发生吻合口狭窄的危险因素,球囊扩张后出血及术后12h内进食是保护因素(P<0.05)。结论食管癌患者颈部吻合术后出现吻合口狭窄可能与术后首次进食时间晚、非线型器械吻合、吻合口瘘、术后持续性低氧血症等因素相关。
Objective To investigate the risk factors for postoperative anastomotic stenosis in esophageal cancer patients.Methods A total of 200 patients who underwent radical esophageal cancer resection at the First Affiliated Hospital of Dali University from July 2015 to June 2024 were selected as subjects.The patients were divided into stenosis group(n=100)and non-stenosis group(n=100)based on whether they had benign anastomotic stenosis.Comparative analyses were conducted regarding the first feeding time,surgical duration,use of non-linear anastomotic devices,and anastomotic leakage in both groups.The independent risk factors for benign postoperative anastomotic stenosis were systematically evaluated.Results Delayed initial postoperative feeding,non-linear anastomotic devices,anastomotic leakage,and persistent postoperative hypoxemia were identified as risk factors for anastomotic stenosis in esophageal cancer patients after neck anastomosis.Balloon dilation-induced bleeding and early postoperative feeding within 12h served as protective factors(P<0.05).Conclusion The development of anastomotic stenosis in esophageal cancer patients following neck anastomosis may be associated with delayed initial feeding,non-linear anastomotic devices,anastomotic leakage,and persistent hypoxemia.
作者
杨文荣
李爱民
杨利杰
李仲华
宋政
杨万春
茶剑媛
YANG Wenrong;LI Aimin;YANG Lijie;LI Zhonghua;SONG Zheng;YANG Wanchun;CHA Jianyuan(Department of Cardiology,the First Affiliated Hospital of Dali University,Dali 671000,Yunnan,China;Department of Gastroenterology,the First Affiliated Hospital of Dali University,Dali 671000,Yunnan,China)
出处
《中国现代医生》
2025年第23期24-27,共4页
China Modern Doctor
基金
云南省大理市2024年科技计划项目(2024KBG139)。
关键词
食管癌
吻合口狭窄
危险因素
Esophageal cancer
Anastomotic stenosis
Risk factors
