摘要
目的比较药物涂层球囊(DCB)与药物洗脱支架(DES)治疗急性ST段抬高型心肌梗死(STEMI)的临床疗效。方法该研究纳入安徽医科大学附属宿州医院2022年7月至2023年9月共118例因急性ST段抬高型心肌梗死行急诊经皮冠状动脉介入(PCI)治疗的住院患者,分为DCB组(46例,DCB治疗)和DES组(72例,DES治疗),比较两组术后6个月内的主要不良心血管事件(MACE)、晚期管腔丢失(LLL)、靶病变血运重建(TLR)、广泛性焦虑自测量表(GAD-7)评分、抑郁症筛查量表(PHQ-9)评分及躯体化症状自评量表评分。结果术后随访6个月,DCB组LLL优于DES组[(0.13±0.09)mm vs.(0.17±0.08)mm](P<0.05)。术后随访6个月,两组TLR(2.2%vs.2.8%)、MACE(6.5%vs.6.9%)比较,差异均无统计学意义(P>0.05)。术后随访6个月,DES组GAD-7评分、PHQ-9评分及躯体化症状自评量表评分均高于DCB组(P<0.05)。结论在术后6个月的随访中,DCB治疗急性STEMI患者的安全性和有效性并不劣于DES,并且在减少患者心理疾病方面优于DES。
【Objective】To compare the clinical efficacy of drug-coated balloon(DCB)and drug-eluting stent(DES)in the treatment for acute ST-segment elevation myocardial infarction(STEMI).【Methods】This study included 118 hospitalized patients with acute ST-segment elevation myocardial infarction who underwent emergency percutaneous coronary intervention(PCI)treatment at Suzhou Municipal Hospital from July 2022 to September 2023.They were divided into an experimental group(46 cases,treated with DCB)and a control group(72 cases,treated with DES).The major adverse cardiovascular events(MACE),late lumen loss(LLL),target lesion revascularization(TLR),Generalized Anxiety Disorder-7(GAD-7)scale score,Patient Health Questionnaire-9(PHQ-9)scale score,and somatic symptom self-assessment scale score within 6 months were compared between the two groups.【Results】During the 6-month follow-up,the DCB group showed superior LLL compared with the DES group(0.13±0.09 mm vs.0.17±0.08 mm,P<0.05).During the 6-month follow-up after surgery,there was no statistically significant difference in TLR(2.2%vs.2.8%)and MACE(6.5%vs.6.9%)between the two groups(P>0.05).During the 6-month follow-up,the DES group showed higher scores in GAD-7,PHQ-9,and self-reported somatic symptoms than the DCB group(P<0.05).【Conclusion】DCB is non-inferior to DES in safety and efficacy for STEMI during the 6-month follow-up after surgery,with additional benefits in reducing psychological distress.
作者
郭学文
李志慧
梁慧
李雪梦
尚亚东
程仁力
GUO Xuewen;LI Zhihui;LIANG Hui;LI Xuemeng;SHANG Yadong;CHENG Renli(Emergency Department,Suzhou Hospital of Anhui Medical University,Suzhou,Anhui 234000,China;Graduate School of Bengbu Medical University,Bengbu,Anhui 233030,China)
出处
《中国医学工程》
2025年第8期61-65,共5页
China Medical Engineering
基金
宿州市卫生健康科研项目(SZWJ2022a043)。
关键词
药物涂层球囊
药物洗脱支架
急性ST段抬高型心肌梗死
双心医学
drug-coated balloon
drug-eluting stents
acute ST-segment elevation myocardial infarction
psychocardiology
