摘要
目的 探讨腹腔镜低位直肠癌根治切除术后无造口生存危险因素。方法 回顾性纳入2019年1月至2022年1月于本院行腹腔镜低位直肠癌根治切除术患者共80例,分析临床特征资料及3年无造口生存情况;比较不同临床特征亚组3年无造口生存率,并采用Cox比例风险模型筛选腹腔镜低位直肠癌根治切除术后无造口生存独立危险因素。结果 全部80例患者中接受造口66例,术后58例行造口还纳,术后3年无造口生存率为84.7%。不同病理T分期亚组、病理N分期亚组及是否接受新辅助治疗亚组3年无造口生存率比较差异有统计学意义(P<0.05)。Cox比例风险模型多因素分析结果显示,病理T分期3期和接受新辅助治疗均是腹腔镜低位直肠癌根治切除术后无造口生存独立危险因素(P<0.05)。结论 腹腔镜低位直肠癌根治切除术后患者如为病理T分期3期或接受新辅助治疗则无造口生存率更低。
Objective To explore the risk factors for stoma free survival after laparoscopic radical resection of low rectal cancer.Methods A retrospective study was conducted on 80 patients who underwent laparoscopic radical resection of low rectal cancer in our hospital from January 2019 to January 2022.Clinical characteristic data and 3-year survival without stoma were analyzed.The 3-year stoma free survival rates of subgroups with different clinical characteristics was compared,and the Cox proportional hazards model was used to screen the independent risk factors for stoma free survival after laparoscopic radical resection of low rectal cancer.Results Among all 80 patients,66 underwent stoma insertion,and 58 patients underwent stoma return after surgery.The 3-year stoma free survival rate was 84.7%.There was a statistically significant difference(P<0.05)in the 3-year stoma free survival rate among different pathological T stage subgroups,pathological N stage subgroups,and subgroups with or without neoadjuvant therapy.The Cox proportional hazards model multivariate analysis results showed that pathological T staging stage 3 and receiving neoadjuvant therapy were independent risk factors for stoma free survival after laparoscopic radical resection of low rectal cancer(P<0.05).Conclusion Patients who undergo laparoscopic radical resection for low rectal cancer and have pathological T stage 3 or receive neoadjuvant therapy have a lower survival rate without stoma.
作者
贝单旦
赵爱青
虞思思
BEI Dandan;ZHAO Aiqing;YU Sisi(Ningbo Medical Center Li Huili Hospital,Zhejiang 315200,China)
出处
《浙江创伤外科》
2025年第8期1427-1429,共3页
Zhejiang Journal of Traumatic Surgery
关键词
腹腔镜
直肠癌
手术
无造口生存
危险因素
Laparoscopy
Rectal cancer
operation
No stoma survival
Risk factors
