摘要
作为全球科技战略发展的重点领域,合成生物学正受到各主要经济体的战略性重视。本文从政策规划、基础研究、技术创新及产业化等多个维度,系统分析了美国、欧洲和中国在合成生物学领域的竞争态势。结果表明,美国在该领域具有显著优势,特别是在基础研究方面拥有大量关键底层技术成果与知识产权。欧洲凭借其独特的区域协同创新模式和产学研深度融合机制,在科研成果转化方面取得显著成效。中国虽然近期在合成生物学领域投入力度持续加大,但在高水平研究产出、高价值专利创造及科技成果转化效率等方面与欧美国家相比仍有待提升。值得指出,在一些特殊领域(体外合成生物学)以及重大应用(如二氧化碳合成淀粉、纤维素变淀粉等)方面,中国已经取得领先地位。基于上述分析,本文建议从完善政策顶层设计、提升企业创新主体地位、突破关键底层技术、优化知识产权布局以及健全产业生态体系等方面着手,推动我国合成生物学产业的高质量发展。
Synthetic biology is an advanced interdisciplinary field that merges biology,engineering,and technology,emerging as a strategic focus for major economies globally.This study offers a detailed comparative assessment of synthetic biology research and development in the United States,Europe,and China.Through systematic analysis of policy infrastructure,research achievements,technological advancements,and industrial applications,we have identified distinct competitive patterns across these regions.Our findings show that the United States maintains a clear leadership position,particularly in fundamental research,with significant technological capabilities and intellectual property assets. Europe has built an effective regional innovation ecosystem, achieving notable success in research commercialization through integrated collaboration among academic, research, and industrial sectors. While China has made substantial recent investments in synthetic biology, there remain opportunities to enhance high-impact research output, valuable patent development, and technology transfer efficiency compared to Western nations. Notably, China has achieved a leading position in specific areas (cell-free synthetic biology) and major applications (such as CO_(2)-to starch synthesis and cellulose-to-starch conversion). Based on the above analysis, this paper recommends promoting the high-quality development of China’s synthetic biology industry through five key approaches: improving top-level policy design, strengthening enterprises’ role as primary innovators, achieving breakthroughs in core technologies, optimizing intellectual property strategy, and enhancing the industrial ecosystem. These recommendations aim to promote the sustainable development of China’s synthetic biology sector. This study provides valuable strategic guidance for decision-makers, researchers, and industry stakeholders, aiding them in navigating the global competitive landscape and making informed decisions regarding the development of synthetic biology.
作者
吴晓燕
宋琪
许睿
丁陈君
陈方
郭勍
张波
WU Xiaoyan;SONG Qi;XU Rui;DING Chenjun;CHEN Fang;GUO Qing;ZHANG Bo(National Science Library(Chengdu),Chinese Academy of Sciences,Chengdu 610299,Sichuan,China;Qingdao Institute of Bioenergy and Bioprocess Technology,Chinese Academy of Sciences,Qingdao 266101,Shandong,China)
出处
《合成生物学》
北大核心
2025年第4期940-955,共16页
Synthetic Biology Journal
基金
山东省合成生物技术产业发展战略研究(202202SDZD05)
2024年中国科学院文献情报能力建设专项项目“科技领域态势分析与服务”(E4290425)。
关键词
合成生物学
合成生物技术
生物制造
生物经济
文献计量分析
synthetic biology
synbio technology
bio-manufacturing
biobased economy
bibliometric analysis
